OMIA 000008-9685 : Acromegaly in Felis catus

See the equivalent entry at NCBI

In other species: dog

Possible human homologues (MIM numbers): 219090 , 102200 , 600634

Mendelian trait/disorder: unknown

Considered a defect: yes

Markers: Scudder et al. (2016) obtained some evidence for a genetic contribution to this disorder in cats: "a nonsynonymous AIP single nucleotide polymorphism in 20% of the acromegalic cat population evaluated, as well as in one of the sibling pairs evaluated". A likely causal mutation has yet to be identified.

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
AIP aryl hydrocarbon receptor interacting protein Felis catus D1 NC_018732.3 (112342256..112349055) AIP Homologene, Ensembl, NCBI gene

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2016 Scudder, C.J., Niessen, S.J., Catchpole, B., Fowkes, R.C., Church, D.B., Forcada, Y. :
Feline hypersomatotropism and acromegaly tumorigenesis: a potential role for the AIP gene. Domest Anim Endocrinol 59:134-139, 2016. Pubmed reference: 28119176. DOI: 10.1016/j.domaniend.2016.11.005.
1993 Abramsogg, A.C.G., Holmberg, D.L., Stewart, W.A., Claffey, F.P. :
Acromegaly in a Cat - Diagnosis by Magnetic Resonance Imaging and Treatment by Cryohypophysectomy Canadian Veterinary Journal - Revue Veterinaire Canadienne 34:682-685, 1993.
1990 Peterson, M.E., Taylor, R.S., Greco, D.S., Nelson, R.W., Randolph, J.F., Foodman, M.S., Moroff, S.D., Morrison, S.A., Lothrop, C.D. :
Acromegaly in 14 Cats Journal of Veterinary Internal Medicine 4:192-201, 1990. Pubmed reference: 2401966.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 30 Jan 2017