OMIA 001279-9823 : Hypotrichosis, recessive in Sus scrofa

See the equivalent entry at NCBI

In other species: dog

Possible human homologues (MIM numbers): 146520 , 146550 , 183849 , 211370 , 246500 , 250460 , 278200 , 301845 , 203655

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Recessive

Considered a defect: yes

Key mutation known: no

Cross-species summary: Recessive form of hair loss.

Inheritance: Roberts and Carroll (1931) provided convincing evidence of autosomal recessive inheritance of hairlessness. It seems very likely that the causative mutation is at a different locus from that which gives rise to "Hypotrichosis, dominant" (MIA 001278) in pigs. However, breeding trials to test non-allelism have not been reported.

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
1931 Roberts, E., Carroll, E. :
The inheritance of hairlessness in swine Journal of Heredity 22:125-132, 1931.
1918 Hart, E.B., Steenbock, H. :
Thyroid hyperplasia and the relation of iodine to the hairless pig malady Journal of Biological Chemistry 33:313-323, 1918.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 14 Feb 2012