OMIA:000750-9615 : Osteochondrosis in Canis lupus familiaris (dog)

In other species: chicken , domestic cat , horse , pig , deer , taurine cattle , indicine cattle (zebu) , sheep , raccoon dog

Categories: Skeleton phene (incl. short stature & teeth)

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 181440 (trait) , 188700 (trait) , 259200 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Abnormal growth ossification centers in young, growing animals. Initially a degeneration/ necrosis followed by regeneration or recalcification. Osteochondrosis (OC) lesions that result is bone or cartilage fragments are called osteochondritis dissecans (OCD) - see OMIA000748.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2005). OMIA:000750-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Hayward, J.J., Todhunter, R.J. :
Common orthopedic traits and screening for breeding programs. Vet Clin North Am Small Anim Pract 53:1013-1029, 2023. Pubmed reference: 37225647. DOI: 10.1016/j.cvsm.2023.04.004.
Lecourtois, C., Baudin-Tréhiou, C., Blond, L. :
Lumbosacral endplate contour defect is frequently observed concurrent with other lumbosacral abnormalities on spinal CT of French Bulldogs. Vet Radiol Ultrasound , 2023. Pubmed reference: 37366604. DOI: 10.1111/vru.13271.
2016 Ohlerth, S., Senn, S., Geissbühler, U., Kircher, P., Flückiger, M. :
Prevalence of humeral head osteochondrosis in the Greater Swiss Mountain dog and the Border Collie in Switzerland. Schweiz Arch Tierheilkd 158:749-754, 2016. Pubmed reference: 27821378. DOI: 10.17236/sat00091.
2012 Dingemanse, W.B., Van Bree, H.J., Duchateau, L., Gielen, I.M. :
Comparison of Clinical and Computed Tomographic Features Between Medial and Lateral Trochlear Ridge Talar Osteochondrosis in Dogs. Vet Surg , 2012. Pubmed reference: 23241002. DOI: 10.1111/j.1532-950X.2012.01069.x.
Hartmann, P., Stock, K.F., Distl, O. :
[Multivariate prediction of breeding values for canine hip and elbow dysplasia as well as humeral osteochondrosis in the Bernese mountain dog]. Berl Munch Tierarztl Wochenschr 125:432-40, 2012. Pubmed reference: 23045807.
2010 Hartmann, P., Stock, KF., Distl, O. :
[Multivariate genetic analysis of canine hip and elbow dysplasia as well as humeral osteochondrosis in the Bernese mountain dog]. Berl Munch Tierarztl Wochenschr 123:488-95, 2010. Pubmed reference: 21141279.
2008 Cook, J.L., Hudson, C.C., Kuroki, K. :
Autogenous osteochondral grafting for treatment of stifle osteochondrosis in dogs. Vet Surg 37:311-21, 2008. Pubmed reference: 18564254. DOI: 10.1111/j.1532-950X.2008.00383.x.
Coopman, F., Verhoeven, G., Saunders, J., Duchateau, L., Van Bree, H. :
Prevalence of hip dysplasia, elbow dysplasia and humeral head osteochondrosis in dog breeds in Belgium. Vet Rec 163:654-8, 2008. Pubmed reference: 19043090.
2007 Ytrehus, B., Carlson, CS., Ekman, S. :
Etiology and pathogenesis of osteochondrosis. Vet Pathol 44:429-48, 2007. Pubmed reference: 17606505. DOI: 10.1354/vp.44-4-429.
2005 Demko, J., McLaughlin, R. :
Developmental orthopedic disease. Vet Clin North Am Small Anim Pract 35:1111-35, v, 2005. Pubmed reference: 16129135. DOI: 10.1016/j.cvsm.2005.05.002.
2002 LaFond, E., Breur, G.J., Austin, C.C. :
Breed susceptibility for developmental orthopedic diseases in dogs Journal of the American Animal Hospital Association 38:467-477, 2002. Pubmed reference: 12220032.
1999 Necas, A., Dvorak, M., Zatloukal, J. :
Incidence of osteochondrosis in dogs and its late diagnosis (vol 68, pg 131, 1999) Acta Veterinaria Brno 68:225, 1999.
Necas, A., Dvorak, M., Zatloukal, J. :
Incidence of osteochondrosis in dogs and its late diagnosis Acta Veterinaria Brno 68:131-139, 1999.
1998 Ekman, S., Carlson, C.S. :
The pathophysiology of osteochondrosis Veterinary Clinics of North America - Small Animal Practice 28:17-32, 1998. Pubmed reference: 9463856.
Fitch, R.B., Beale, B.S. :
Osteochondrosis of the canine tibiotarsal joint Veterinary Clinics of North America - Small Animal Practice 28:95 ff., 1998.
Harari, J. :
Osteochondrosis - preface Veterinary Clinics of North America - Small Animal Practice 28:R 9, 1998.
Harari, J. :
Osteochondrosis of the femur Veterinary Clinics of North America - Small Animal Practice 28:87 ff., 1998.
Kippenes, H., Johnston, G. :
Diagnostic imaging of osteochondrosis Veterinary Clinics of North America - Small Animal Practice 28:137 ff., 1998.
Leighton, R.L. :
Historical perspectives of osteochondrosis Veterinary Clinics of North America - Small Animal Practice 28:1 ff., 1998.
Richardson, D.C., Zentek, J. :
Nutrition and osteochondrosis Veterinary Clinics of North America - Small Animal Practice 28:115 ff., 1998.
Snaps, F.R., Heimann, M., Saunders, J., Beths, T., Balligand, M., Breton, L. :
Osteochondrosis of the sacral bone in a mastiff dog Veterinary Record 143:476-477, 1998. Pubmed reference: 9829306.
Vanbree, H.J.J., Vanryssen, B. :
Diagnostic and surgical arthroscopy in osteochondrosis lesions [Review] Veterinary Clinics of North America - Small Animal Practice 28:161 ff., 1998.
1997 Harari, J. :
Identifying and managing osteochondrosis in dogs Veterinary Medicine 92:508-509, 1997.
Toth, J., Dioszegi, Z., Fenyves, B. :
New form of osteochondrosis - apophyseolysis of tuber calcanei in young rottweiler and dobermann dogs (severs-disease) [Hungarian] Magyar Allatorvosok Lapja 119:399-402, 1997.
Vanbree, H.J.J., Vanryssen, B. :
The value of arthroscopy in the diagnosis and treatment of osteochondrosis in the dog [Dutch] Tijdschrift voor Diergeneeskunde 122:710-714, 1997. Pubmed reference: 9534814.
1996 Jeffcott, L.B., Savage, C.J. :
Nutrition and the development of osteochondrosis (dyschondroplasia) Pferdeheilkunde 12:338-342, 1996.
Zentek, J., Dammrich, K., Meyer, H. :
Pathogenesis of orthopaedic bone diseases due to the nutrition (osteochondrosis syndrome) of growing dogs in large breeds .2. [Review] [Hungarian] Magyar Allatorvosok Lapja 51:561-564, 1996.
Zentek, J., Nolte, I. :
Osteochondrosis in a 9 month old Bernese mountain dog - case report .2. [Hungarian] Magyar Allatorvosok Lapja 51:566-569, 1996.
1995 Thomson, M.J., Robins, G.M. :
Osteochondrosis of the elbow - a review of the pathogenesis and a new approach to treatment Australian Veterinary Journal 72:375-378, 1995. Pubmed reference: 8599569.
Zentek, J., Nolte, I. :
Osteochondroses in a nine month old Bernese mountain dog [German] Kleintierpraxis 40:879 ff., 1995.
1994 Vanbree, H. :
Evaluation of Subchondral Lesion Size in Osteochondrosis of the Scapulohumeral Joint in Dogs Journal of the American Veterinary Medical Association 204:1472-1474, 1994. Pubmed reference: 8050973.
1993 Fox, S. :
Osteochondrosis - How to Identify and Treat Its Manifestations in Dogs - Introduction Veterinary Medicine 88:114, 1993.
Fox, S.M., Walker, A.M. :
Identifying and Treating the Primary Manifestations of Osteochondrosis of the Elbow Veterinary Medicine 88:132, 1993.
Fox, S.M., Walker, A.M. :
The Etiopathogenesis of Osteochondrosis Veterinary Medicine 88:116, 1993.
Vanbree, H. :
Comparison of the Diagnostic Accuracy of Positive-Contrast Arthrography and Arthrotomy in Evaluation of Osteochondrosis Lesions in the Scapulohumeral Joint in Dogs Journal of the American Veterinary Medical Association 203:84-88, 1993. Pubmed reference: 8407466.
Vanbree, H., Degryse, H., Vanryssen, B., Ramon, F., Desmidt, M. :
Pathologic Correlations with Magnetic Resonance Images of Osteochondrosis Lesions in Canine Shoulders Journal of the American Veterinary Medical Association 202:1099-1105, 1993. Pubmed reference: 8473223.
Vanryssen, B., Vanbree, H., Missinne, S. :
Successful Arthroscopic Treatment of Shoulder Osteochondrosis in the Dog Journal of Small Animal Practice 34:521-528, 1993.
1992 Vanbree, H., Vanryssen, B., Desmidt, M. :
Osteochondrosis Lesions of the Canine Shoulder - Correlation of Positive Contrast Arthrography and Arthroscopy Veterinary Radiology & Ultrasound 33:342-347, 1992.
1991 Smith, C.W. :
Osteochondrosis in the Dog - Diagnosis, Treatment, and Prognosis Canine Practice 16:15, 1991.
Watson, A.D.J., Miller, A.C., Allan, G.S., Davis, P.E., Howlett, C.R. :
Osteochondrodysplasia in Bull Terrier Littermates Journal of Small Animal Practice 32:312-317, 1991.
1990 Wisner, E.R., Berry, C.R., Morgan, J.P., Pool, R.R., Wind, A.P., Vasseur, P.B. :
Osteochondrosis of the Lateral Trochlear Ridge of the Talus in 7 Rottweiler Dogs Veterinary Surgery 19:435-439, 1990. Pubmed reference: 2264281.
1986 Bergsten, G., Nordin, M. :
[Osteochondrosis as a cause of claims in a population of insured dogs] Svensk Veterinartidning 38:97-100, 1986.
1955 Ullrich, ?. :
Osteochondrosis of the femur in young dogs Berliner und Munchener Tierarztliche Wochenschrift 68:287-288, 1955.

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  • Created by Frank Nicholas on 06 Sep 2005