OMIA:001273-9940 : Resistance/susceptibility to Fasciola gigantica in Ovis aries (sheep)

Categories: Liver/biliary system phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Species-specific description: Roberts et al. (1997b) reported the results of assessing resistance to a type of liver fluke, Fasciola gigantica, in the segregating generations of a cross between the highly resistant Indonesian Thin Tail (ITT) and the susceptible St Croix breeds of sheep. The data were suggestive of a gene of large effect on resistance.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Breed: Priangan, Indonesia (Sheep) (VBO_0016011).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2005). OMIA:001273-9940: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2015 Bishop, S.C. :
Genetic resistance to infections in sheep. Vet Microbiol 181:2-7, 2015. Pubmed reference: 26260859. DOI: 10.1016/j.vetmic.2015.07.013.
1997 Roberts, J.A., Estuningsih, E., Widjayanti, S., Wiedosari, E., Partoutomo, S., Spithill, T.W. :
Resistance of Indonesian Thin Tail sheep against Fasciola gigantica and F-hepatica Veterinary Parasitology 68:69-78, 1997. Pubmed reference: 9066053.
Roberts, J.A., Widjayanti, S., Estuningsih, E., Hetzel, D.J. :
Evidence for a major gene determining the resistance of Indonesian Thin Tail sheep against Fasciola gigantica Veterinary Parasitology 68:309-314, 1997. Pubmed reference: 9106952.

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  • Created by Frank Nicholas on 06 Sep 2005