OMIA:001322-93934 : Feather colour, roux in Coturnix japonica (Japanese quail) |
Categories: Pigmentation phene
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 115501 (gene) , 612271 (trait)
Links to MONDO diseases: No links.
Mendelian trait/disorder: yes
Mode of inheritance: Sex-linked
Considered a defect: no
Key variant known: yes
Year key variant first reported: 2007
Species-specific symbol: r
Molecular basis: Nadeau et al. (2007) showed that this plumage mutant corresponds to a SNP (giving rise to Phe282Ser) in the gene for TYRP1 - orthologous to the classic brown coat-colour locus in mammals.
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Associated gene:
| Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
|---|---|---|---|---|---|---|
| TYRP1 | tyrosinase-related protein 1 | Coturnix japonica | Z | NC_029547.1 (27668114..27687084) | TYRP1 | Homologene, Ensembl , NCBI gene |
Variants
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WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
Since October 2021, OMIA includes a semiautomated lift-over pipeline to facilitate updates of genomic positions to a recent reference genome position. These changes to genomic positions are not always reflected in the ‘acknowledgements’ or ‘verbal description’ fields in this table.
| OMIA Variant ID | Breed(s) | Variant Phenotype | Gene | Allele | Type of Variant | Source of Genetic Variant | Reference Sequence | Chr. | g. or m. | c. or n. | p. | Verbal Description | EVA ID | Inferred EVA rsID | Year Published | PubMed ID(s) | Acknowledgements |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 258 | Feather colour, roux | TYRP1 | missense | Naturally occurring variant | c.845T>C | p.(F282S) | 2007 | 18028514 |
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2012). OMIA:001322-93934: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2009 | Minvielle, F., Cecchi, T., Passamonti, P., Gourichon, D., Renieri, C. : |
| Plumage colour mutations and melanins in the feathers of the Japanese quail: a first comparison. Anim Genet 40:971-4, 2009. Pubmed reference: 19496774. DOI: 10.1111/j.1365-2052.2009.01929.x. | |
| 2007 | Nadeau, NJ., Mundy, NI., Gourichon, D., Minvielle, F. : |
| Association of a single-nucleotide substitution in TYRP1 with roux in Japanese quail (Coturnix japonica). Anim Genet 38:609-13, 2007. Pubmed reference: 18028514. DOI: 10.1111/j.1365-2052.2007.01667.x. | |
| 2003 | Minvielle, F., Gourichon, D., Monvoisin, JL. : |
| Effects of two-locus combinations, using the roux, lavender, and beige mutations, on plumage color of Japanese quail. J Hered 94:517-22, 2003. Pubmed reference: 14691319. | |
| 2001 | Minvielle, F., Ito, S., Inoue-Murayama, M., Mizutani, M., Wakasugi, N. : |
| Genetic analyses of plumage color mutations on the Z chromosome of Japanese quail. J Hered 91:499-501, 2001. Pubmed reference: 11218091. | |
| 2000 | Minvielle, F., Gandemer, G., Maeda, Y., Leborgne, C., Hirigoyen, E., Boulay, M. : |
| Carcase characteristics of a heavy Japanese quail line under introgression with the roux gene British Poultry Science 41:41-45, 2000. Pubmed reference: 10821521. DOI: 10.1080/00071660086385. | |
| 1999 | Minvielle, F., Hirigoyen, E., Boulay, M. : |
| Associated effects of the roux plumage color mutation on growth, carcass traits, egg production, and reproduction of Japanese quail Poultry Science 78:1479-1484, 1999. Pubmed reference: 10560817. |
Edit History
- Created by Frank Nicholas on 24 Jan 2008
- Changed by Frank Nicholas on 08 Sep 2011
- Changed by Frank Nicholas on 12 Oct 2011
- Changed by Frank Nicholas on 09 Dec 2011
- Changed by Frank Nicholas on 21 Mar 2012