OMIA:001418-9615 : Cricopharyngeal dysfunction in Canis lupus familiaris (dog) |
Categories: Digestive / alimentary phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: yes
Mode of inheritance: Autosomal recessive
Considered a defect: yes
Key variant known: no
Species-specific name: CD
Species-specific description: As reported by Davidson et al. (2004), "The CD phenotype was determined by videofluoroscopy, and dogs were classified as affected if the upper esophageal sphincter (UES) did not open, if there were morphologic abnormalities of the UES, or if opening of the UES was delayed for > or = 6 videofluoroscopic frames (0.2 seconds) after closure of the epiglottis."
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Breed:
Golden Retriever (Dog) (VBO_0200610).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2022). OMIA:001418-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
Reference
2004 | Davidson, AP., Pollard, RE., Bannasch, DL., Marks, SL., Hornof, WJ., Famula, TR. : |
Inheritance of cricopharyngeal dysfunction in Golden Retrievers. Am J Vet Res 65:344-9, 2004. Pubmed reference: 15027684. |
Edit History
- Created by Frank Nicholas on 25 Oct 2005
- Changed by Frank Nicholas on 18 Jun 2013
- Changed by Imke Tammen2 on 23 Oct 2022