OMIA:001696-9031 : Earlobe pigmentation in Gallus gallus (chicken)

Categories: Pigmentation phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: no

Mode of inheritance: Multifactorial

Considered a defect: no

Key variant known: no

History: This trait was first described by Warren (1928).

Mapping: Wragg et al. (2012) mapped this trait to several regions, concluding that it is "sex-linked and polygenic". Guo et al. (2023): "compared the genomes of multiple domestic chicken breeds with red and white earlobes to identify the differentiated regions between groups of breeds differing in earlobe color. This was done using a selective sweep mapping approach based on whole-genome sequence data. The most significant selective sweep was identified on chromosome 11, where the white earlobe chicken breeds originated from Mediterranean share a common haplotype, and where multiple candidate genes are located. The most plausible functional candidate gene is the Melanocortin 1 Receptor (MC1R) ... ."

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:001696-9031: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Guo, Y., Rubin, C.J., Rönneburg, T., Wang, S., Li, H., Hu, X., Carlborg, Ö. :
Whole-genome selective sweep analyses identifies the region and candidate gene associated with white earlobe color in Mediterranean chickens. Poult Sci 103:103232, 2023. Pubmed reference: 37980749. DOI: 10.1016/j.psj.2023.103232.
2016 Nie, C., Zhang, Z., Zheng, J., Sun, H., Ning, Z., Xu, G., Yang, N., Qu, L. :
Genome-wide association study revealed genomic regions related to white/red earlobe color trait in the Rhode Island Red chickens. BMC Genet 17:115, 2016. Pubmed reference: 27496128. DOI: 10.1186/s12863-016-0422-1.
2012 Wragg, D., Mwacharo, J.M., Alcalde, J.A., Hocking, P.M., Hanotte, O. :
Analysis of genome-wide structure, diversity and fine mapping of Mendelian traits in traditional and village chickens. Heredity (Edinb) 109:6-18, 2012. Pubmed reference: 22395157. DOI: 10.1038/hdy.2012.9.
1928 Warren, D.C. :
Inheritance of Earlobe Color in Poultry. Genetics 13:470-87, 1928. Pubmed reference: 17246562.

Edit History


  • Created by Frank Nicholas on 01 Jul 2012
  • Changed by Frank Nicholas on 17 Oct 2012
  • Changed by Imke Tammen2 on 21 Nov 2023