In other species: dog , horse

Categories: Skeleton phene (incl. short stature & teeth)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Key variant is published: no

Cross-species summary: "A joint disorder caused by blood deprivation in the subchondral bone causing the subchondral bone to die in a process called avascular necrosis. The bone is then reabsorbed by the body, leaving the articular cartilage it supported prone to damage. The result is fragmentation (dissection) of both cartilage and bone, and the free movement of these osteochondral fragments within the joint space, causing pain and further damage" [HPO:0010886] Osteochondritis dissecans (OCD) is sometimes called osteochondrosis dissecans and is a more severe form of Osteochondrosis (OC) - see OMIA000750.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing