OMIA:001894-9615 : Cervical vertebral compressive myelopathy in Canis lupus familiaris (dog) |
In other species: mountain zebra , horse , sheep
Categories: Nervous system phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: Also known as hereditary ataxia
Species-specific name: Cervical spondylomyelopathy; wobbler syndrome
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Breeds:
Borzoi (Dog) (VBO_0200197),
Doberman Pinscher (Dog) (VBO_0200442),
Great Dane (Dog) (VBO_0200623),
Mastiff (Dog) (VBO_0200867).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:001894-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2024 | Danciu, C.G., Formoso Prado, S., Fitzgerald, E. : |
| Imaging features of occipito-atlanto-axial joint malformation in a young dog. J Small Anim Pract , 2024. Pubmed reference: 38568753. DOI: 10.1111/jsap.13720. | |
| Pilkington, E.J., De Decker, S., Skovola, E., Cloquell Miro, A., Gutierrez Quintana, R., Faller, K.M.E., Aguilera Padros, A., Goncalves, R. : | |
| Prevalence, clinical presentation, and etiology of myelopathies in 224 juvenile dogs. J Vet Intern Med , 2024. Pubmed reference: 38483074. DOI: 10.1111/jvim.17045. | |
| 2023 | Wade, C.M., Nuttall, R., Liu, S. : |
| Comprehensive analysis of geographic and breed-purpose influences on genetic diversity and inherited disease risk in the Doberman dog breed. Canine Med Genet 10:7, 2023. Pubmed reference: 37277858. DOI: 10.1186/s40575-023-00130-3. | |
| 2015 | Martin-Vaquero, P., da Costa, R.C. : |
| Body conformation in Great Danes with and without clinical signs of cervical spondylomyelopathy. Vet J 203:219-22, 2015. Pubmed reference: 25555338. DOI: 10.1016/j.tvjl.2014.12.003. | |
| 2011 | De Decker, S., Gielen, IM., Duchateau, L., van Bree, HJ., Waelbers, T., Bavegems, V., Van Ham, LM. : |
| Morphometric dimensions of the caudal cervical vertebral column in clinically normal Doberman Pinschers, English Foxhounds and Doberman Pinschers with clinical signs of disk-associated cervical spondylomyelopathy. Vet J , 2011. Pubmed reference: 21257325. DOI: 10.1016/j.tvjl.2010.12.017. | |
| 2010 | da Costa, RC. : |
| Cervical spondylomyelopathy (wobbler syndrome) in dogs. Vet Clin North Am Small Anim Pract 40:881-913, 2010. Pubmed reference: 20732597. DOI: 10.1016/j.cvsm.2010.06.003. | |
| 2002 | Davidson, E.B., Bahr, R.J., Ritchey, J.W., Lorenz, M.D. : |
| Hindlimb ataxia in an English bulldog Veterinary Medicine 97:265-+, 2002. | |
| 2000 | Sumano, E., Bermudez, E., Obregon, K. : |
| Treatment of wobbler syndrome in dogs with electroacupuncture Deutsche Tierarztliche Wochenschrift 107:231-235, 2000. Pubmed reference: 10916938. | |
| 1999 | McKee, W.M., Butterworth, S.J., Scott, H.W. : |
| Management of cervical spondylopathy-associated intervertebral disc protrusions using metal washers in 78 dogs Journal of Small Animal Practice 40:465-472, 1999. Pubmed reference: 10587923. | |
| 1998 | Queen, J.P., Coughlan, A.R., May, C., Bennett, D., Penderis, J. : |
| Management of disc-associated wobbler syndrome with a partial slot fenestration and position screw technique Journal of Small Animal Practice 39:131-136, 1998. Pubmed reference: 9551381. | |
| 1995 | Burbidge, H.M. : |
| A review of wobbler syndrome in the Doberman Pinscher [Review] Australian Veterinary Practitioner 25:147-156, 1995. | |
| Sharp, N.J.H., Cofone, M., Robertson, I.D., Decarlo, A., Smith, G.K., Thrall, D.E. : | |
| Computed tomography in the evaluation of caudal cervical spondylomyelopathy of the Doberman Pinscher Veterinary Radiology & Ultrasound 36:100-108, 1995. | |
| 1994 | Burbidge, H.M., Pfeiffer, D.U., Blair, H.T. : |
| Canine Wobbler-Syndrome - A Study of the Dobermann-Pinscher in New-Zealand New Zealand Veterinary Journal 42:221-228, 1994. | |
| Denis, B., Marescaux, L. : | |
| Heredity of a Medullary Cervical Ataxia Syndrome (Wobbler Syndrome) in the Mastiff Recueil de Medecine Veterinaire 170:245-247, 1994. | |
| Seim, H.B. : | |
| Wobbler Syndrome in the Doberman-Pinscher (Reprinted) Canine Practice 19:23-26, 1994. | |
| Thilagar, S., Mohammed, M.S.D.M., Gopal, M.S. : | |
| Cervical Spondylomyelopathy (Wobbler Syndrome) in the Dog Indian Veterinary Journal 71:918-920, 1994. | |
| 1993 | Mandigers, P.J.J., Vannes, J.J., Knol, B.W., Ubbink, G.J., Gruys, E. : |
| Hereditary Kooiker Dog Ataxia Tijdschrift Voor Diergeneeskunde 118:S65, 1993. Pubmed reference: 8480326. | |
| 1992 | Sharp, N.J.H., Wheeler, S.J., Cofone, M. : |
| Radiological Evaluation of Wobbler Syndrome - Caudal Cervical Spondylomy-Elopathy Journal of Small Animal Practice 33:491-499, 1992. | |
| 1988 | Jaggy, A., Gaillard, C., Lang, J., Vandevelde, M. : |
| Hereditary cervical spondylopathy (wobbler syndrome) in the Borzoi dog Journal of the American Animal Hospital Association 24:453-460, 1988. | |
| 1962 | Bjorck, G., Mair, W., Olsson, S.G., Sourander, P. : |
| Hereditary ataxia in Fox Terriers Acta Neuropathologia 1 supplement:45-48, 1962. | |
| 1957 | Bjorck, G., Dryendahl, S., Olsson, S.E. : |
| Hereditary ataxia in smooth haired Fox Terriers Veterinary Record 69:871-876, 1957. |
Edit History
- Created by Carrie Finno on 11 Dec 2013
- Changed by Carrie Finno on 11 Dec 2013
- Changed by Imke Tammen2 on 07 Jun 2023