OMIA:002362-9925 : Fecundity, GDF9-related in Capra hircus (goat) |
Categories: Reproductive system phene
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 601918 (gene) , 618014 (trait)
Links to MONDO diseases: No links.
Mendelian trait/disorder: yes
Mode of inheritance: Autosomal
Considered a defect: no
Key variant known: yes
Year key variant first reported: 2016
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Breeds:
Bengal (Goat) (VBO_0000731),
Shanbei White Cashmere, China (Goat) (VBO_0009450).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below
Associated gene:
| Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
|---|---|---|---|---|---|---|
| GDF9 | growth differentiation factor 9 | Capra hircus | 7 | NC_030814.1 (66023938..66028657) | GDF9 | Homologene, Ensembl , NCBI gene |
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2022). OMIA:002362-9925: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2023 | Song, T., Liu, Y., Cuomu, R., Tan, Y., A Wang, C., De, J., Cao, X., Zeng, X. : |
| Polymorphisms analysis of BMP15, GDF9 and BMPR1B in Tibetan Cashmere Goat (Capra hircus). Genes (Basel) 14, 2023. Pubmed reference: 37239462. DOI: 10.3390/genes14051102. | |
| 2021 | Aboelhassan, D.M., Darwish, A.M., Ali, N.I., Ghaly, I.S., Farag, I.M. : |
| A study on mutation points of GDF9 gene and their association with prolificacy in Egyptian small ruminants. J Genet Eng Biotechnol 19:85, 2021. Pubmed reference: 34097165. DOI: 10.1186/s43141-021-00181-8. | |
| Das, A., Shaha, M., Gupta, M.D., Dutta, A., Miazi, O.F. : | |
| Polymorphism of fecundity genes (BMP15 and GDF9) and their association with litter size in Bangladeshi prolific Black Bengal goat. Trop Anim Health Prod 53:230, 2021. Pubmed reference: 33772358. DOI: 10.1007/s11250-021-02679-2. | |
| 2020 | Bi, Y., Li, J., Wang, X., He, L., Lan, K., Qu, L., Lan, X., Song, X., Pan, C. : |
| Two novel rare strongly linked missense SNPs (P27R and A85G) within the GDF9 gene were significantly associated with litter size in Shaanbei White Cashmere (SBWC) goats. Front Vet Sci 7:406, 2020. Pubmed reference: 32851004. DOI: 10.3389/fvets.2020.00406. | |
| 2019 | Ghoreishi, H., Fathi-Yosefabad, S., Shayegh, J., Barzegari, A. : |
| Identification of mutations in BMP15 and GDF9 genes associated with prolificacy of Markhoz goats. Arch Anim Breed 62:565-570, 2019. Pubmed reference: 31807668. DOI: 10.5194/aab-62-565-2019. | |
| 2018 | Wang, X., Yang, Q., Wang, K., Yan, H., Pan, C., Chen, H., Liu, J., Zhu, H., Qu, L., Lan, X. : |
| Two strongly linked single nucleotide polymorphisms (Q320P and V397I) in GDF9 gene are associated with litter size in cashmere goats. Theriogenology 125:115-121, 2018. Pubmed reference: 30414564. DOI: 10.1016/j.theriogenology.2018.10.013. | |
| 2016 | Zhao, J., Liu, S., Zhou, X., Zhang, R., Li, Y., Wang, X., Chen, Y. : |
| A non-synonymous mutation in GDF9 is highly associated with litter size in cashmere goats. Anim Genet 47:630-1, 2016. Pubmed reference: 27298140. DOI: 10.1111/age.12447. | |
| 2013 | Pramod, R.K., Sharma, S.K., Singhi, A., Pan, S., Mitra, A. : |
| Differential ovarian morphometry and follicular expression of BMP15, GDF9 and BMPR1B influence the prolificacy in goat. Reprod Domest Anim 48:803-9, 2013. Pubmed reference: 23581245. DOI: 10.1111/rda.12165. |
Edit History
- Created by Imke Tammen2 on 25 Jun 2021
- Changed by Imke Tammen2 on 25 Jun 2021
- Changed by Imke Tammen2 on 21 May 2022