Categories: Nervous system phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Mode of inheritance: Probably autosomal recessive

Considered a defect: yes

Species-specific name: This condition is clinically indistinguishable from daft lamb disease (OMIA 000177-9940 : Cerebellar cortical atrophy in Ovis aries), but differs by the absence of noticeable changes to the cerebellum or other parts of the CNS. In addition to typical congenital neurological clinical science, skeletal fragility and a progressive myopathy was noted.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Breed: Border Leicester (Sheep) (VBO_0001347).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below