OMIA:002426-10042 : Coat colour, dominant spot in Peromyscus maniculatus (North American deer mouse) |
Categories: Pigmentation phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: yes
Mode of inheritance: Autosomal dominant
Considered a defect: yes
Key variant known: no
Inheritance: S/S homozygotes are likely embryonic lethal
Mapping: Shang et al. (2020) "conduct a candidate gene linkage analysis for the Dominant spot trait and determined that Dominant spot is linked to a region of chromosome 20 that contains a strong candidate gene, Sox10. During the linkage analysis, we found that the spot size varied quantitively in affected Peromyscus based on genetic background."
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2021). OMIA:002426-10042: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2020 | Shang, Z., Horovitz, D.J., McKenzie, R.H., Keisler, J.L., Felder, M.R., Davis, S.W. : |
| Using genomic resources for linkage analysis in Peromyscus with an application for characterizing Dominant Spot. BMC Genomics 21:622, 2020. Pubmed reference: 32912160. DOI: 10.1186/s12864-020-06969-1. | |
| 2013 | Vrana, P.B., Shorter, K.R., Szalai, G., Felder, M.R., Crossland, J.P., Veres, M., Allen, J.E., Wiley, C.D., Duselis, A.R., Dewey, M.J., Dawson, W.D. : |
| Peromyscus (deer mice) as developmental models. Wiley Interdiscip Rev Dev Biol 3:211-30, 2013. Pubmed reference: 24896658. DOI: 10.1002/wdev.132. | |
| 1936 | Feldman, H.W. : |
| Piebald characters of the deer mouse. J Heredity 27:301, 1936. |
Edit History
- Created by Imke Tammen2 on 16 Sep 2021
- Changed by Imke Tammen2 on 16 Sep 2021