OMIA 000540-255217 : Hypotrichosis in Balaenoptera omurai

In other species: macaques , dog , domestic cat , bottlenosed dolphin , beluga whale , minke whale , pig , cattle , sheep , rabbit , golden hamster , Mongolian gerbil , meadow voles , domestic guinea pig , Indo-Pacific finless porpoise , long-beaked common dolphin , Yangtze River dolphin , American mink

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 146520 , 146550 , 183849 , 211370 , 246500 , 250460 , 278200

Mendelian trait/disorder: unknown

Considered a defect: no

Year key variant first reported: 2013

Cross-species summary: Also known as Hairless

Molecular basis: Chen et al. (2013) reported evidence that the HR gene in cetaceans, including Balaenoptera omurai, has degenerated into a non-functional pseudogene, which is consistent with the hairlessness of this species.

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
HR Balaenoptera omurai - no genomic information (-..-) HR Ensembl

Reference


2013 Chen, Z., Wang, Z., Xu, S., Zhou, K., Yang, G. :
Characterization of hairless (Hr) and FGF5 genes provides insights into the molecular basis of hair loss in cetaceans. BMC Evol Biol 13:34, 2013. Pubmed reference: 23394579. DOI: 10.1186/1471-2148-13-34.

Edit History


  • Created by Frank Nicholas on 19 Aug 2013
  • Changed by Frank Nicholas on 19 Aug 2013