OMIA:001230-9685 : Ovotesticular DSD (Disorder of Sexual Development) in Felis catus

In other species: horse , cattle , wood lemming , Japanese medaka , dog , rabbit , pig , Western roe deer

Categories: Reproductive system phene

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 400044 (trait) , 300018 (trait) , 612965 (trait) , 154230 (trait) , 613080 (trait) , 613762 (trait) , 233420 (trait) , 614279 (trait) , 480000 (gene)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Previously known as Sex reversal: XY female, SRY-negative. The present name (ovotesticular DSD) corresponds to the recommendations on nomenclature for disorders of sexual development (DSD) proposed by Lee et al. (Pediatrics 2006;118;e488; DOI: 10.1542/peds.2006-0738).

History: The first case of this disorder in cats was reported by Schlafer et al. (2010).


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2020 Szczerbal, I., Switonski, M. :
Genetic disorders of sex development in cats: An update. Anim Reprod Sci 216:106353, 2020. Pubmed reference: 32414464 . DOI: 10.1016/j.anireprosci.2020.106353.
2015 PieĊ„kowska-Schelling, A., Becker, D., Pineroli, B., Schelling, C. :
Ein Fall von SRY positiver Sex-Umkehr bei einer Hauskatze [A case of SRY positive sex reversal in a domestic cat]. Schweiz Arch Tierheilkd 157:157-9, 2015. Pubmed reference: 26753328 . DOI: 10.17236/sat00013.
2014 Nowacka-Woszuk, J., Szczerbal, I., Salamon, S., Kociucka, B., Jackowiak, H., Prozorowska, E., Slaska, B., Rozanska, D., Orzelski, M., Ochota, M., Dzimira, S., Lipiec, M., Nizanski, W., Switonski, M. :
Testicular disorder of sex development in four cats with a male karyotype (38,XY; SRY-positive). Anim Reprod Sci 151:42-8, 2014. Pubmed reference: 25455261 . DOI: 10.1016/j.anireprosci.2014.10.001.
2011 Schlafer, D.H., Valentine, B., Fahnestock, G., Froenicke, L., Grahn, R.A., Lyons, L.A., Meyers-Wallen, V.N. :
A case of SRY-positive 38,XY true hermaphroditism (XY sex reversal) in a cat. Vet Pathol 48:817-22, 2011. Pubmed reference: 20861501 . DOI: 10.1177/0300985810382093.

Edit History

  • Created by Frank Nicholas on 26 Sep 2010
  • Changed by Imke Tammen2 on 22 Aug 2021