OMIA:002709-9091 : Feather colour, white, OCA2-related in Coturnix coturnix (common quail)

Categories: Pigmentation phene

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 611409 (gene) , 203200 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: no

Species-specific description: Zhang et al. (2023): "The Beijing white quail is a new mutant strain in feather color and originated from Korean quail (Coturnix coturnix) in the 1970s. Young Beijing white quail have light yellow feathers and dark yellow stripes on their backs (Zhang et al, 2013). After first molting, the feathers become pure white, albeit with light yellow stripes on the back and both wings of the quail ... . The eyes of the Beijing white quail are red, which is obviously different from the black eyes of the Korean quail (Wu et al, 2018). ... we provide evidence that variations in an intron of HERC2 and upstream of OCA2 can decrease OCA2 mRNA expression. In turn, this effect likely underlies the diluted plumage color and red eyes in Beijing white quail."

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:002709-9091: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Zhang, X., Qi, Y., Pang, Y., Yuan, B., Li, X. :
Identification of polymorphisms in the HERC2-OCA2 gene locus and their association with feather color in quail. J Poult Sci 60:2023013, 2023. Pubmed reference: 37234755. DOI: 10.2141/jpsa.2023013.
2018 Wu, Y., Zhang, Y., Hou, Z., Fan, G., Pi, J., Sun, S., Chen, J., Liu, H., Du, X., Shen, J., Hu, G., Chen, W., Pan, A., Yin, P., Chen, X., Pu, Y., Zhang, H., Liang, Z., Jian, J., Zhang, H., Wu, B., Sun, J., Chen, J., Tao, H., Yang, T., Xiao, H., Yang, H., Zheng, C., Bai, M., Fang, X., Burt, D.W., Wang, W., Li, Q., Xu, X., Li, C., Yang, H., Wang, J., Yang, N., Liu, X., Du, J. :
Population genomic data reveal genes related to important traits of quail. Gigascience 7, 2018. Pubmed reference: 29762663. DOI: 10.1093/gigascience/giy049.
2013 Zhang, X.H., Pang, Y.Z., Zhao, S.J., Xu, H.W., Li, Y.L., Xu, Y., Guo, Z., Wang, D.D. :
The relationship of plumage colours with MC1R (Melanocortin 1 Receptor) and ASIP (Agouti Signaling Protein) in Japanese quail (Coturnix coturnix japonica). Br Poult Sci 54:306-11, 2013. Pubmed reference: 23639082. DOI: 10.1080/00071668.2013.780122.

Edit History

  • Created by Imke Tammen2 on 29 May 2023
  • Changed by Imke Tammen2 on 29 May 2023