In other species: domestic cat , horse

Categories: Skeleton phene (incl. short stature & teeth)

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 106600 (trait) , 206780 (trait) , 211370 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Congenital absence of some or all of the teeth; includes hypodontia

Inheritance: "The results of integrated segregation analysis indicated heterogeneous genetic control of different forms of hypodontia. The geneses of different premolars in dogs have been demonstrated to be described by different models of inheritance: the absence of the second premolars can be described by the recessive major-gene model, whereas the agenesis of the fourth premolars have a more complex genetic mechanism and cannot be described by the model of a simple major-gene control." (Aksenovich et al., 2004)

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing