OMIA:000147-9793 : Brachygnathia in Equus asinus (ass (donkey)) |
In other species: dog , horse , pig , llama , giraffe , taurine cattle , sheep , alpaca
Categories: Craniofacial phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: Congenital abnormal shortness of the mandible (lower jaw), resulting in protrusion of the maxilla (upper jaw).
Markers: Using a comparative candidate gene strategy, based on evidence from humans, Rodrigues et al. (2013) could not identify any marker in the MATN1 gene (encoding Matrilin-1) to be associated with this disorder.
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Breed:
Zamorano-Leonés-Spain, Spain (Ass) (VBO_0001829).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2014). OMIA:000147-9793: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
Reference
2013 | Rodrigues, J.B., Araújo, S., Guedes-Pinto, H., San Roman, F., Viegas, C., Bastos, E. : |
Analysis of new Matrilin-1 gene variants in a case-control study related to dental malocclusions in Equus asinus. Gene 522:70-4, 2013. Pubmed reference: 23558247. DOI: 10.1016/j.gene.2013.03.084. |
Edit History
- Created by Frank Nicholas on 29 Jan 2014