OMIA:000424 : Goitre, familial

Categories: Endocrine / exocrine gland phene (incl mammary gland)

Possible human homologues (MIM numbers): 274700 (trait) , 188450 (gene)

Links to MONDO diseases:

Cross-species summary: Goitre is the enlargement of the thyroid gland, causing a swelling in the front of the neck. The condition can develop due to nutritional iodine deficiencies but familial forms of this disorder have been identified in several species. The molecular basis been determined for familial goitre in cattle and goats. Also spelt goiter.

Species in which this phene is found:
chicken (Gallus gallus)
dog (Canis lupus familiaris)
American black bear (Ursus americanus)
domestic cat (Felis catus)
pig (Sus scrofa)
taurine cattle (Bos taurus)
goat (Capra hircus)
sheep (Ovis aries)
golden hamster (Mesocricetus auratus)
bongo (Tragelaphus eurycerus)
water buffalo (Bubalus bubalis)

Edit History


  • Created by Frank Nicholas on 03 May 2005
  • Changed by Frank Nicholas on 18 Apr 2012
  • Changed by Frank Nicholas on 19 Sep 2012
  • Changed by Frank Nicholas on 10 Oct 2012
  • Changed by Imke Tammen2 on 26 Sep 2021
  • Changed by Imke Tammen2 on 03 Feb 2023
  • Changed by Imke Tammen2 on 19 Sep 2023