OMIA:000576-9913 : Knobbed acrosome in Bos taurus (taurine cattle) |
In other species: dog , horse , pig , sheep
Categories: Reproductive system phene
Possibly relevant human trait(s) and/or gene(s) (MIM number): 606165 (gene)
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: The presence of a protrusion (knob) on the acrosome (cap) of a sperm. Associated with sterility. Also known as Knobbed Acrosome Defect (KAD)
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2012). OMIA:000576-9913: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2005 | Chenoweth, P.J. : |
| Genetic sperm defects. Theriogenology 64:457-68, 2005. Pubmed reference: 15993939. DOI: 10.1016/j.theriogenology.2005.05.005. | |
| 2002 | Thundathil, J., Palasz, AT., Barth, AD., Mapletoft, RJ. : |
| Plasma membrane and acrosomal integrity in bovine spermatozoa with the knobbed acrosome defect. Theriogenology 58:87-102, 2002. Pubmed reference: 12182368. | |
| 2000 | Thundathil, J., Meyer, R., Palasz, AT., Barth, AD., Mapletoft, RJ. : |
| Effect of the knobbed acrosome defect in bovine sperm on IVF and embryo production. Theriogenology 54:921-34, 2000. Pubmed reference: 11097045. DOI: 10.1016/S0093-691X(00)00402-7. | |
| 1985 | Mitchell, JR., Senger, PL., Rosenberger, JL. : |
| Distribution and retention of spermatozoa with acrosomal and nuclear abnormalities in the cow genital tract. J Anim Sci 61:956-67, 1985. Pubmed reference: 4066546. | |
| 1983 | Blom, E. : |
| The ultrastructure of some characteristic sperm defects and a proposal for a new classification of the bull spermiogram Nordisk Veterinary Medicine 25:383-391, 1983. | |
| 1976 | Cran, D.G., Dott, H.M. : |
| The ultrastructure of knobbed bull spermatozoa Journal of Reproduction and Fertility 47:407-408, 1976. Pubmed reference: 957345. | |
| 1962 | Blom, E., Birch-Andersen, A. : |
| Ultrastructure of the sterilizing 'knobbed-sperm' defect in the bull Nature 194:989-990, 1962. |
Edit History
- Created by Frank Nicholas on 06 Sep 2005
- Changed by Frank Nicholas on 21 May 2012