OMIA:001279-9823 : Hypotrichosis, recessive in Sus scrofa (pig)

In other species: dog

Categories: Integument (skin) phene

Possibly relevant human trait(s) and/or gene(s) (MIM number): 607591 (gene)

Links to MONDO diseases: No links.

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal recessive

Considered a defect: yes

Key variant known: no

Cross-species summary: Recessive form of lack of hair growth

Inheritance: Roberts and Carroll (1931) provided convincing evidence of autosomal recessive inheritance of hairlessness. It seems very likely that the causative mutation is at a different locus from that which gives rise to "Hypotrichosis, dominant" (MIA 001278) in pigs. However, breeding trials to test non-allelism have not been reported.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2012). OMIA:001279-9823: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

1931 Roberts, E., Carroll, E. :
The inheritance of hairlessness in swine Journal of Heredity 22:125-132, 1931.
1918 Hart, E.B., Steenbock, H. :
Thyroid hyperplasia and the relation of iodine to the hairless pig malady Journal of Biological Chemistry 33:313-323, 1918.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 14 Feb 2012