OMIA:001813-9615 : Haemangiosarcoma in Canis lupus familiaris (dog) |
In other species: African hunting dog , domestic cat , horse , pig , taurine cattle , sheep , cockatiel , orange-winged amazon parrot
Categories: Neoplasm
Possibly relevant human trait(s) and/or gene(s) (MIM number): 148000 (trait)
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: Hemangiosarcoma
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Breeds:
Doberman Pinscher (Dog) (VBO_0200442),
German Shepherd Dog (Dog) (VBO_0200577),
Golden Retriever (Dog) (VBO_0200610).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:001813-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2023 | De Nardi, A.B., de Oliveira Massoco Salles Gomes, C., Fonseca-Alves, C.E., de Paiva, F.N., Linhares, L.C.M., Carra, G.J.U., Dos Santos Horta, R., Ruiz Sueiro, F.A., Jark, P.C., Nishiya, A.T., de Carvalho Vasconcellos, C.H., Ubukata, R., Batschinski, K., Sobral, R.A., Fernandes, S.C., Biondi, L.R., De Francisco Strefezzi, R., Matera, J.M., Rangel, M.M.M., Dos Anjos, D.S., Brunner, C.H.M., Laufer-Amorim, R., Cadrobbi, K.G., Cirillo, J.V., Martins, M.C., de Paula Reis Filho, N., Silva Lessa, D.F., Portela, R., Scarpa Carneiro, C., Ricci Lucas, S.R., Fukumasu, H., Feliciano, M.A.R., Gomes Quitzan, J., Dagli, M.L.Z. : |
| Diagnosis, prognosis, and treatment of canine hemangiosarcoma: A review based on a consensus organized by the Brazilian Association of Veterinary Oncology, ABROVET. Cancers (Basel) 15:2025, 2023. Pubmed reference: 37046686. DOI: 10.3390/cancers15072025. | |
| Estabrooks, T., Gurinovich, A., Pietruska, J., Lewis, B., Harvey, G., Post, G., Lambert, L., Miller, A., Rodrigues, L., White, M.E., Lopes, C., London, C.A., Megquier, K. : | |
| Identification of genomic alterations with clinical impact in canine splenic hemangiosarcoma. Vet Comp Oncol 21:623-633, 2023. Pubmed reference: 37734854. DOI: 10.1111/vco.12925. | |
| Heishima, K., Aketa, N., Heishima, M., Kawachi, A. : | |
| Hemangiosarcoma in dogs as a potential non-rodent animal model for drug discovery research of angiosarcoma in humans. Front Oncol 13:1250766, 2023. Pubmed reference: 38130992. DOI: 10.3389/fonc.2023.1250766. | |
| Hillman, A., Swafford, B., Delavenne, C., Fieten, H., Boerkamp, K., Tietje, K. : | |
| Descriptive analysis of haemangiosarcoma occurrence in dogs enrolled in the Golden Retriever lifetime study. Vet Comp Oncol 21:700-708, 2023. Pubmed reference: 37635246. DOI: 10.1111/vco.12933. | |
| Kapturska, K.M., Pawlak, A. : | |
| New molecular targets in canine hemangiosarcoma-Comparative review and future of the precision medicine. Vet Comp Oncol 21:357-377, 2023. Pubmed reference: 37308243. DOI: 10.1111/vco.12917. | |
| Klosowski, M., Haines, L., Alfino, L., McMellen, A., Leibowitz, M., Regan, D. : | |
| Naturally occurring canine sarcomas: Bridging the gap from mouse models to human patients through cross-disciplinary research partnerships. Front Oncol 13:1130215, 2023. Pubmed reference: 37035209. DOI: 10.3389/fonc.2023.1130215. | |
| Pimentel, P.A.B., Giuliano, A., Bęczkowski, P.M., Horta, R.D.S. : | |
| Molecular profile of canine hemangiosarcoma and potential novel therapeutic targets. Vet Sci 10:387, 2023. Pubmed reference: 37368773. DOI: 10.3390/vetsci10060387. | |
| Sabattini, S., Baldassarro, V.A., Zaccone, R., Calzà, L., Giardino, L., Vascellari, M., Lorenzini, L., Moretti, M., Marconato, L. : | |
| Dysregulated miRNAs in a canine model of haemangiosarcoma metastatic to the brain. Vet Comp Oncol , 2023. Pubmed reference: 38112225. DOI: 10.1111/vco.12949. | |
| Suzuki, T., Henshaw, M.J., Yanagi, T., Aoshima, K. : | |
| Current understanding of comparative pathology and prospective research approaches for canine hemangiosarcoma. Res Vet Sci 167:S0034-5288(23)00371-5:105120, 2023. Pubmed reference: 38150941. DOI: 10.1016/j.rvsc.2023.105120. | |
| Wade, C.M., Nuttall, R., Liu, S. : | |
| Comprehensive analysis of geographic and breed-purpose influences on genetic diversity and inherited disease risk in the Doberman dog breed. Canine Med Genet 10:7, 2023. Pubmed reference: 37277858. DOI: 10.1186/s40575-023-00130-3. | |
| 2021 | Evans, J.M., Parker, H.G., Rutteman, G.R., Plassais, J., Grinwis, G.C.M., Harris, A.C., Lana, S.E., Ostrander, E.A. : |
| Multi-omics approach identifies germline regulatory variants associated with hematopoietic malignancies in retriever dog breeds. PLoS Genet 17:e1009543, 2021. Pubmed reference: 33983928. DOI: 10.1371/journal.pgen.1009543. | |
| Griffin, M.A., Culp, W.T.N., Rebhun, R.B. : | |
| Canine and feline haemangiosarcoma. Vet Rec :e585, 2021. Pubmed reference: 34213807. DOI: 10.1002/vetr.585. | |
| 2020 | Kim, J.H. : |
| PIK3CA mutations matter for cancer in dogs. Res Vet Sci 133:39-41, 2020. Pubmed reference: 32932196. DOI: 10.1016/j.rvsc.2020.09.001. | |
| 2016 | Anwar, S.h., Yanai, T., Sakai, H. : |
| Overexpression of Peroxiredoxin 6 Protects Neoplastic Cells against Apoptosis in Canine Haemangiosarcoma. J Comp Pathol 155:29-39, 2016. Pubmed reference: 27306414. DOI: 10.1016/j.jcpa.2016.05.002. | |
| Yoo, S., Kim, J., Myung, H.W., Woo, S., Chung, D.J., Lee, A.J., Kim, H.J., DO, S.H., Kim, H.Y. : | |
| Primary intrapelvic hemangiosarcoma in a dog. J Vet Med Sci , 2016. Pubmed reference: 27746404. DOI: 10.1292/jvms.16-0186. | |
| 2015 | Tonomura, N., Elvers, I., Thomas, R., Megquier, K., Turner-Maier, J., Howald, C., Sarver, A.L., Swofford, R., Frantz, A.M., Ito, D., Mauceli, E., Arendt, M., Noh, H.J., Koltookian, M., Biagi, T., Fryc, S., Williams, C., Avery, A.C., Kim, J.H., Barber, L., Burgess, K., Lander, E.S., Karlsson, E.K., Azuma, C., Modiano, J.F., Breen, M., Lindblad-Toh, K. : |
| Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers. PLoS Genet 11:e1004922, 2015. Pubmed reference: 25642983. DOI: 10.1371/journal.pgen.1004922. | |
| 2014 | Thomas, R., Borst, L., Rotroff, D., Motsinger-Reif, A., Lindblad-Toh, K., Modiano, J.F., Breen, M. : |
| Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma. Chromosome Res , 2014. Pubmed reference: 24599718. DOI: 10.1007/s10577-014-9406-z. | |
| 2013 | Alvarez, F.J., Hosoya, K., Lara-Garcia, A., Kisseberth, W., Couto, G. : |
| VAC Protocol for Treatment of Dogs with Stage III Hemangiosarcoma. J Am Anim Hosp Assoc , 2013. Pubmed reference: 24051260. DOI: 10.5326/JAAHA-MS-5954. | |
| Bellumori, T.P., Famula, T.R., Bannasch, D.L., Belanger, J.M., Oberbauer, A.M. : | |
| Prevalence of inherited disorders among mixed-breed and purebred dogs: 27,254 cases (1995-2010). J Am Vet Med Assoc 242:1549-55, 2013. Pubmed reference: 23683021. DOI: 10.2460/javma.242.11.1549. | |
| Dobson, J.M. : | |
| Breed-predispositions to cancer in pedigree dogs. ISRN Vet Sci 2013:941275, 2013. Pubmed reference: 23738139. DOI: 10.1155/2013/941275. | |
| Tsuji, N., Furukawa, S., Ozaki, K. : | |
| Cutaneous hemangiosarcoma in a dog. J Toxicol Pathol 26:193-5, 2013. Pubmed reference: 23914061. DOI: 10.1293/tox.26.193. | |
| Yamamoto, S., Hoshi, K., Hirakawa, A., Chimura, S., Kobayashi, M., Machida, N. : | |
| Epidemiological, Clinical and Pathological Features of Primary Cardiac Hemangiosarcoma in Dogs: A Review of 51 Cases. J Vet Med Sci , 2013. Pubmed reference: 23811814. | |
| 2012 | Asa, S.A., Murai, A., Murakami, M., Hoshino, Y., Mori, T., Maruo, K., Khater, A., El-Sawak, A., el-Aziz, E.A., Yanai, T., Sakai, H. : |
| Expression of platelet-derived growth factor and its receptors in spontaneous canine hemangiosarcoma and cutaneous hemangioma. Histol Histopathol 27:601-7, 2012. Pubmed reference: 22419024. | |
| Guinan, J., Fischetti, A., Garate, A.P., Chalhoub, S. : | |
| Primary peri-aortic hemangiosarcoma in a dog. Can Vet J 53:1214-8, 2012. Pubmed reference: 23633719. | |
| 2011 | Haeussler, D.J., Rodríguez, L.M., Wilkie, D.A., Premanandan, C. : |
| Primary central corneal hemangiosarcoma in a dog. Vet Ophthalmol 14:133-6, 2011. Pubmed reference: 21366830. DOI: 10.1111/j.1463-5224.2010.00849.x. | |
| Mun, A., Lee, E.M., Kim, A.Y., Lee, E.J., Hong, I.H., Jeong, K.S. : | |
| Canine hemangiosarcoma in a female Jindo dog. Lab Anim Res 27:361-3, 2011. Pubmed reference: 22232648. DOI: 10.5625/lar.2011.27.4.361. | |
| Shiu, K.B., Flory, A.B., Anderson, C.L., Wypij, J., Saba, C., Wilson, H., Kurzman, I., Chun, R. : | |
| Predictors of outcome in dogs with subcutaneous or intramuscular hemangiosarcoma. J Am Vet Med Assoc 238:472-9, 2011. Pubmed reference: 21320017. DOI: 10.2460/javma.238.4.472. | |
| 2010 | Fawcett, A., Phillips, A., Billson, M. : |
| Ocular hemangiosarcoma in a husky. Compend Contin Educ Vet 32:E8, 2010. Pubmed reference: 23705189. | |
| Tamburini, B.A., Phang, T.L., Fosmire, S.P., Scott, M.C., Trapp, S.C., Duckett, M.M., Robinson, S.R., Slansky, J.E., Sharkey, L.C., Cutter, G.R., Wojcieszyn, J.W., Bellgrau, D., Gemmill, R.M., Hunter, L.E., Modiano, J.F. : | |
| Gene expression profiling identifies inflammation and angiogenesis as distinguishing features of canine hemangiosarcoma. BMC Cancer 10:619, 2010. Pubmed reference: 21062482. DOI: 10.1186/1471-2407-10-619. | |
| 2009 | Tamburini, B.A., Trapp, S., Phang, T.L., Schappa, J.T., Hunter, L.E., Modiano, J.F. : |
| Gene expression profiles of sporadic canine hemangiosarcoma are uniquely associated with breed. PLoS One 4:e5549, 2009. Pubmed reference: 19461996. DOI: 10.1371/journal.pone.0005549. | |
| 2007 | Sargan, D. : |
| Haemangiosarcoma in German shepherd dogs. Vet Rec 160:672, 2007. Pubmed reference: 17496285. | |
| Yonemaru, K., Sakai, H., Murakami, M., Kodama, A., Mori, T., Yanai, T., Maruo, K., Masegi, T. : | |
| The significance of p53 and retinoblastoma pathways in canine hemangiosarcoma. J Vet Med Sci 69:271-8, 2007. Pubmed reference: 17409643. | |
| 2006 | Lamerato-Kozicki, A.R., Helm, K.M., Jubala, C.M., Cutter, G.C., Modiano, J.F. : |
| Canine hemangiosarcoma originates from hematopoietic precursors with potential for endothelial differentiation. Exp Hematol 34:870-8, 2006. Pubmed reference: 16797414. DOI: 10.1016/j.exphem.2006.04.013. | |
| 2005 | Dickerson, E.B., Thomas, R., Fosmire, S.P., Lamerato-Kozicki, A.R., Bianco, S.R., Wojcieszyn, J.W., Breen, M., Helfand, S.C., Modiano, J.F. : |
| Mutations of phosphatase and tensin homolog deleted from chromosome 10 in canine hemangiosarcoma. Vet Pathol 42:618-32, 2005. Pubmed reference: 16145208. DOI: 10.1354/vp.42-5-618. | |
| 2004 | Fosmire, S.P., Dickerson, E.B., Scott, A.M., Bianco, S.R., Pettengill, M.J., Meylemans, H., Padilla, M., Frazer-Abel, A.A., Akhtar, N., Getzy, D.M., Wojcieszyn, J., Breen, M., Helfand, S.C., Modiano, J.F. : |
| Canine malignant hemangiosarcoma as a model of primitive angiogenic endothelium. Lab Invest 84:562-72, 2004. Pubmed reference: 15064773. DOI: 10.1038/labinvest.3700080. | |
| Schultheiss, P.C. : | |
| A retrospective study of visceral and nonvisceral hemangiosarcoma and hemangiomas in domestic animals. J Vet Diagn Invest 16:522-6, 2004. Pubmed reference: 15586567. | |
| 2003 | Smith, A.N. : |
| Hemangiosarcoma in dogs and cats. Vet Clin North Am Small Anim Pract 33:533-52, vi, 2003. Pubmed reference: 12852235. | |
| 2002 | Mayr, B., Zwetkoff, S., Schaffner, G., Reifinger, M. : |
| Tumour suppressor gene p53 mutation in a case of haemangiosarcoma of a dog. Acta Vet Hung 50:157-60, 2002. Pubmed reference: 12113170. DOI: 10.1556/AVet.50.2002.2.4. | |
| 2001 | Clifford, C.A., Hughes, D., Beal, M.W., Mackin, A.J., Henry, C.J., Shofer, F.S., Sorenmo, K.U. : |
| Plasma vascular endothelial growth factor concentrations in healthy dogs and dogs with hemangiosarcoma. J Vet Intern Med 15:131-5, 2001. Pubmed reference: 11300596. | |
| 1998 | Wood, C.A., Moore, A.S., Gliatto, J.M., Ablin, L.A., Berg, R.J., Rand, W.M. : |
| Prognosis for dogs with stage I or II splenic hemangiosarcoma treated by splenectomy alone: 32 cases (1991-1993). J Am Anim Hosp Assoc 34:417-21, 1998. Pubmed reference: 9728473. | |
| 1994 | Ward, H., Fox, L.E., Calderwood-Mays, M.B., Hammer, A.S., Couto, C.G. : |
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Edit History
- Created by Frank Nicholas on 22 May 2013
- Changed by Imke Tammen2 on 16 Sep 2021
- Changed by Imke Tammen2 on 07 Jun 2023