OMIA:001923-9615 : Spinal intradural arachnoid cyst in Canis lupus familiaris (dog)

Categories: Nervous system phene

Possibly relevant human trait(s) and/or gene(s) (MIM number): 182990 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: fluid-filled sac that occurs on the arachnoid membrane that covers the spinal cord

Inheritance: Rohdin et al. (2014) reported that "Seven related young pugs were diagnosed with cervical spinal intradural arachnoid cysts by magnetic resonance imaging (n=6) and myelography (n=1)" and that "Pedigree analysis suggested a genetic predisposition for spinal arachnoid cysts in this family of pugs"

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Breed: Pug (Dog) (VBO_0201089).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2014). OMIA:001923-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

Reference

2014 Rohdin, C., Nyman, H.T., Wohlsein, P., Hultin Jäderlund, K. :
Cervical spinal intradural arachnoid cysts in related, young pugs. J Small Anim Pract 55:229-34, 2014. Pubmed reference: 24372140. DOI: 10.1111/jsap.12167.

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  • Created by Frank Nicholas on 23 Jun 2014