OMIA:001923-9615 : Spinal intradural arachnoid cyst in Canis lupus familiaris (dog) |
Categories: Nervous system phene
Possibly relevant human trait(s) and/or gene(s) (MIM number): 182990 (trait)
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: fluid-filled sac that occurs on the arachnoid membrane that covers the spinal cord
Inheritance: Rohdin et al. (2014) reported that "Seven related young pugs were diagnosed with cervical spinal intradural arachnoid cysts by magnetic resonance imaging (n=6) and myelography (n=1)" and that "Pedigree analysis suggested a genetic predisposition for spinal arachnoid cysts in this family of pugs"
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Breed:
Pug (Dog) (VBO_0201089).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2014). OMIA:001923-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
Reference
2014 | Rohdin, C., Nyman, H.T., Wohlsein, P., Hultin Jäderlund, K. : |
Cervical spinal intradural arachnoid cysts in related, young pugs. J Small Anim Pract 55:229-34, 2014. Pubmed reference: 24372140. DOI: 10.1111/jsap.12167. |
Edit History
- Created by Frank Nicholas on 23 Jun 2014