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OMIA:002237-8090 : Coat colour, few melanophore in Oryzias latipes (Japanese medaka)

Categories: Pigmentation phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal recessive

Considered a defect: no

Key variant known: yes

Year key variant first reported: 2020

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
kitlga Oryzias latipes 6 NC_019864.2 (2512710..2469124) kitlga Homologene, Ensembl , NCBI gene

Variants

By default, variants are sorted chronologically by year of publication, to provide a historical perspective. Readers can re-sort on any column by clicking on the column header. Click it again to sort in a descending order. To create a multiple-field sort, hold down Shift while clicking on the second, third etc relevant column headers.

WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.

Since October 2021, OMIA includes a semiautomated lift-over pipeline to facilitate updates of genomic positions to a recent reference genome position. These changes to genomic positions are not always reflected in the ‘acknowledgements’ or ‘verbal description’ fields in this table.

OMIA Variant ID Breed(s) Variant Phenotype Gene Allele Type of Variant Source of Genetic Variant Reference Sequence Chr. g. or m. c. or n. p. Verbal Description EVA ID Inferred EVA rsID Year Published PubMed ID(s) Acknowledgements
1152 Few melanophore kitlga insertion, gross (>20) Naturally occurring variant Otsuki et al. (2020): "the phenotype of fm medaka is attributable to insertion of a Tcb1-like transposon at the kitlga locus" 2020 31757930
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Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2020). OMIA:002237-8090: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Wagatsuma, T., Suzuki, E., Shiotsu, M., Sogo, A., Nishito, Y., Ando, H., Hashimoto, H., Petris, M.J., Kinoshita, M., Kambe, T. :
Pigmentation and TYRP1 expression are mediated by zinc through the early secretory pathway-resident ZNT proteins. Commun Biol 6:403, 2023. Pubmed reference: 37072620. DOI: 10.1038/s42003-023-04640-5.
2020 Otsuki, Y., Okuda, Y., Naruse, K., Saya, H. :
Identification of kit-ligand a as the gene responsible for the medaka pigment cell mutant few melanophore. G3 (Bethesda) 10:311-9, 2020. Pubmed reference: 31757930. DOI: 10.1534/g3.119.400561.

Edit History


  • Created by Frank Nicholas on 30 Jan 2020
  • Changed by Frank Nicholas on 30 Jan 2020