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OMIA:002670-9913 : Lactoglobulin, beta in Bos taurus (taurine cattle)

In other species: ass (donkey) , indicine cattle (zebu)

Categories: Endocrine / exocrine gland phene (incl mammary gland)

Links to MONDO diseases: No links.

Mendelian trait/disorder: yes

Considered a defect: no

Key variant known: no

Species-specific description: This phene includes references to studies involving gene edited or genetically modified organisms (GMO). PAEP is the HGNC approved gene symbol for beta-lactglobulin (BLG).

Genetic engineering: Yes - in addition to the occurrence of natural variants, variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
PAEP progestagen-associated endometrial protein Bos taurus 11 NC_037338.1 (103255756..103260862) PAEP Homologene, Ensembl , NCBI gene

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:002670-9913: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2024 Boushaba, N., Tabet-Aoul, N. :
Allele and genotype frequencies of β-lactoglobulin gene using PCR-RFLP in Algerian local cattle populations. Mol Biol Res Commun 13:43-49, 2024. Pubmed reference: 38164367. DOI: 10.22099/mbrc.2023.47661.1841.
Ghavi Hossein-Zadeh, N. :
Evidence of additive genetic variation for major milk proteins in dairy cows: A meta-analysis. J Anim Breed Genet , 2024. Pubmed reference: 38230949. DOI: 10.1111/jbg.12850.
Zhang, W., Zheng, S., Zhu, H., Lu, J., Zhang, Y., Hettinga, K., Pang, X., Lyu, J., Zhang, S. :
Effects of protein genetic variants on their phosphorylation levels, milk composition, milk proteome, and milk coagulation ability in Chinese Holstein bovine milk. Int J Biol Macromol :S0141-8130(24)00647-0:129844, 2024. Pubmed reference: 38316325. DOI: 10.1016/j.ijbiomac.2024.129844.
2023 Gim, G.M., Eom, K.H., Kwon, D.H., Jung, D.J., Kim, D.H., Yi, J.K., Ha, J.J., Lee, J.H., Lee, S.B., Son, W.J., Yum, S.Y., Lee, W.W., Jang, G. :
Generation of double knockout cattle via CRISPR-Cas9 ribonucleoprotein (RNP) electroporation. J Anim Sci Biotechnol 14:103, 2023. Pubmed reference: 37543609. DOI: 10.1186/s40104-023-00902-8.

Edit History


  • Created by Imke Tammen2 on 12 Aug 2023
  • Changed by Imke Tammen2 on 12 Aug 2023
  • Changed by Imke Tammen2 on 18 Dec 2023