OMIA:002808-9823 : Coat colour, white belt, EDNRB-related in Sus scrofa (pig) |
Categories: Pigmentation phene
Possibly relevant human trait(s) and/or gene(s) (MIM number): 131244 (gene)
Links to MONDO diseases: No links.
Mendelian trait/disorder: yes
Considered a defect: no
Key variant known: no
Species-specific name: Chinese belted, two end black
Mapping: Ai et al. (2013) "identified the strongest signal of directional selection at the EDNRB loci in Chinese belted pigs, supporting EDNRB as a promising candidate gene for the white belt coat color in Chinese pigs."
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Breeds:
Huazhong Two-end Black - Jianli, China (Pig) (VBO_0012788),
Huazhong Two-End Black - Shaziling, China (Pig) (VBO_0012786),
Huazhong Two-End Black - Tongcheng, China (Pig) (VBO_0012787),
Jinhua, China (Pig) (VBO_0012796).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below
Associated gene:
| Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
|---|---|---|---|---|---|---|
| EDNRB | endothelin receptor type B | Sus scrofa | 11 | NC_010453.5 (50102879..50073300) | EDNRB | Homologene, Ensembl , NCBI gene |
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2024). OMIA:002808-9823: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2024 | Xu, Z., Wu, J., Zhang, Y., Qiao, M., Zhou, J., Feng, Y., Li, Z., Sun, H., Lin, R., Song, Z., Zhao, H., Li, L., Chen, N., Li, Y., Oyelami, F.O., Peng, X., Mei, S. : |
| Genome-wide detection of selection signatures in Jianli pigs reveals novel cis-regulatory haplotype in EDNRB associated with two-end black coat color. BMC Genomics 25:23, 2024. Pubmed reference: 38166718. DOI: 10.1186/s12864-023-09943-9. | |
| 2023 | Giovannini, S., Strillacci, M.G., Bagnato, A., Albertini, E., Sarti, F.M. : |
| Genetic and phenotypic characteristics of belted pig reeds: A review. Animals (Basel) 13:3072, 2023. Pubmed reference: 37835678. DOI: 10.3390/ani13193072. | |
| 2022 | Zheng, S., Xu, P., Wu, Z., Zhang, H., Li, D., Liu, S., Liu, B., Ren, J., Chen, H., Huang, M. : |
| Genetic structure and domestication footprints of the tusk, coat color, and ear morphology in East Chinese pigs. J Genet Genomics 49:1053-1063, 2022. Pubmed reference: 35413463. DOI: 10.1016/j.jgg.2022.03.011. | |
| 2020 | Huang, M., Yang, B., Chen, H., Zhang, H., Wu, Z., Ai, H., Ren, J., Huang, L. : |
| The fine-scale genetic structure and selection signals of Chinese indigenous pigs. Evol Appl 13:458-475, 2020. Pubmed reference: 31993089. DOI: 10.1111/eva.12887. | |
| 2018 | Zhang, Z., Xiao, Q., Zhang, Q.Q., Sun, H., Chen, J.C., Li, Z.C., Xue, M., Ma, P.P., Yang, H.J., Xu, N.Y., Wang, Q.S., Pan, Y.C. : |
| Genomic analysis reveals genes affecting distinct phenotypes among different Chinese and western pig breeds. Sci Rep 8:13352, 2018. Pubmed reference: 30190566. DOI: 10.1038/s41598-018-31802-x. | |
| 2015 | Wang, C., Wang, H., Zhang, Y., Tang, Z., Li, K., Liu, B. : |
| Genome-wide analysis reveals artificial selection on coat colour and reproductive traits in Chinese domestic pigs. Mol Ecol Resour 15:414-24, 2015. Pubmed reference: 25132237. DOI: 10.1111/1755-0998.12311. | |
| 2013 | Ai, H., Huang, L., Ren, J. : |
| Genetic diversity, linkage disequilibrium and selection signatures in chinese and Western pigs revealed by genome-wide SNP markers. PLoS One 8:e56001, 2013. Pubmed reference: 23409110. DOI: 10.1371/journal.pone.0056001. |
Edit History
- Created by Imke Tammen2 on 08 Dec 2023
- Changed by Imke Tammen2 on 08 Dec 2023
- Changed by Imke Tammen2 on 09 Jan 2024