Welcome to OMIA
Online Mendelian Inheritance in Animals (OMIA) is a catalogue/compendium of inherited disorders, other (single-locus) traits, and associated genes and variants in 795 (mostly vertebrate) animal species (other than human and mouse and rats and zebrafish and western clawed frog, which have their own resources) co-authored by curator Associate Professor Imke Tammen and founder Professor Frank Nicholas of the University of Sydney, Australia, with help from many people over the years. OMIA information is stored in a database that contains textual information and references, as well as links to relevant PubMed and Gene records at the NCBI, to OMIM, Ensembl, Mondo Disease Ontology and the Vertebrate Breed Ontology (VBO).
OMIA is manually curated by a team of specialists. If you see an error or wish to submit an entry, please contact us.
To join the OMIA Support Group, register at OMIA Support Group.
From 1st September 2011, the OMIA ID is binomial, comprising an OMIA phene ID and the NCBI species taxonomy ID.
The table below shows summary information for key domesticated species. A more detailed table covering additional species, as well as information based on phene categories (aligned with Mammalian Phenotype and Mondo ontology terms), can be found under the Browse tab.
To report a suspected or confirmed inherited disease in Australian animals for surveillance, visit the Anstee Hub for Inherited Diseases in Animals (AHIDA).
OMIA has been a free internet resource for over 30 years, with much of the crucial curation work done on a volunteer basis. Please consider donating to help pay for maintenance, upgrades and curation time.
We have recently launched the Pioneers of Mendelian Inheritance in Animals project (PMIA), an exploration of the history of research into Mendelian inheritance in animals.
Summary
| dog | taurine cattle | cat | pig | sheep | horse | chicken | rabbit | goat | Other | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Traits (phenes) | |||||||||||
| All traits: disease and non-disease | 1023 | 750 | 476 | 430 | 353 | 333 | 290 | 161 | 142 | 2153 | 6111 |
| All single-gene traits: disease and non-disease | 461 | 328 | 153 | 154 | 136 | 73 | 143 | 89 | 30 | 585 | 2152 |
| with at least one known likely causal variant | 381 | 227 | 125 | 79 | 71 | 57 | 60 | 30 | 20 | 325 | 1375 |
| Single-gene diseases | 415 | 289 | 125 | 123 | 98 | 57 | 100 | 71 | 14 | 251 | 1543 |
| with at least one known likely causal variant | 349 | 208 | 104 | 65 | 52 | 45 | 34 | 23 | 9 | 113 | 1002 |
| Chromosomal phenes | 9 | 24 | 10 | 15 | 12 | 17 | 12 | 5 | 6 | 82 | 192 |
| Potential models for human disease | 658 | 374 | 296 | 238 | 155 | 176 | 96 | 95 | 68 | 1058 | 3214 |
| Variants (mutations) | |||||||||||
| All known likely causal variants for all single-gene traits: disease and non-disease | 601 | 301 | 216 | 77 | 98 | 120 | 79 | 25 | 23 | 285 | 1825 |
| All known likely causal variants for single-gene diseases | 547 | 270 | 167 | 59 | 57 | 102 | 39 | 15 | 10 | 91 | 1357 |
