OMIA:000030-9615 : Alopecia, generic in Canis lupus familiaris (dog) |
In other species: chicken , Rhesus monkey , giant panda , domestic cat , white-tailed deer , taurine cattle , sheep , American red squirrel
Categories: Integument (skin) phene
Links to possible relevant human trait(s) and/or gene(s) in OMIM: 104000 (trait) , 104110 (trait) , 203655 (trait) , 612421 (trait) , 610753 (trait) , 300042 (trait) , 109200 (trait) , 300710 (trait)
Mendelian trait/disorder: yes
Disease-related: yes
Key variant known: no
Cross-species summary: Absence of hair, wool or feathers due to loss of hair (not in reference to primary genetic hair, wool, feather-lessness)
Species-specific description: includes references relating to alopecia X, hair cycle arrest
Breed:
Pomeranian (Dog) (VBO_0201043).
Breeds in which the phene has been documented. (If a likely causal variant has been documented for the phene, see the variant table breeds in which the variant has been reported).
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2024). OMIA:000030-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2024 | Brennan, E., Juhola, J., Ferguson, E.A., Loeffler, A., Cerundolo, R., Hendricks, A., Bond, R. : |
| Hair fragility (trichorrhexis nodosa) in alopecic Pomeranian dogs. Vet Dermatol , 2024. Pubmed reference: 39344877. DOI: 10.1111/vde.13296. | |
| Deleporte, S., Prelaud, P., Laffort, C. : | |
| Alopecia X in a cloned Pomeranian dog. Vet Dermatol 35:194-196, 2024. Pubmed reference: 38169070. DOI: 10.1111/vde.13234. | |
| Lopes, C.E.B., Lundberg, A., White, A., Neto, R.L.A.L.T. : | |
| Alopecia in a Boxer. J Am Vet Med Assoc :1-3, 2024. Pubmed reference: 39019061. DOI: 10.2460/javma.24.04.0286. | |
| 2023 | Della Salda, L., Bongiovanni, L., Massimini, M., Romanucci, M., Vercelli, A., Colosimo, A., Di Matteo, R., Defourny, S.V.P. : |
| p63 immunoexpression in hair follicles of normal and alopecia X-affected skin of Pomeranian dogs. Vet Dermatol 34:567-575, 2023. Pubmed reference: 37518946. DOI: 10.1111/vde.13195. | |
| 2022 | Kang, Y.H., Hyun, J.E., Hwang, C.Y. : |
| The number of mitochondrial DNA mutations as a genetic feature for hair cycle arrest (alopecia X) in Pomeranian dogs. Vet Dermatol 33:545-552, 2022. Pubmed reference: 36000586. DOI: 10.1111/vde.13114. | |
| Neradilová, S., Schauer, A.M., Hayward, J.J., Brunner, M.A.T., Bohutínská, M., Jagannathan, V., Connell, L.B., Boyko, A.R., Welle, M.M., Černá Bolfíková, B. : | |
| Genomic and transcriptomic characterization of atypical recurrent flank alopecia in the Cesky Fousek. Genes (Basel) 13:650, 2022. Pubmed reference: 35456456. DOI: 10.3390/genes13040650. | |
| 2019 | May, E.R., Frank, L.A., Sula, M.M. : |
| Description and characterization of a hair coat disorder in schipperkes. Vet Dermatol 30:36-e10, 2019. Pubmed reference: 30556622. DOI: 10.1111/vde.12711. | |
| 2018 | Layne, E.A., Richmond, R.V. : |
| Deslorelin implant treatment for hair cycle arrest (Alopecia X) in two intact male Keeshonden. J Am Anim Hosp Assoc 54:231-234, 2018. Pubmed reference: 29757666. DOI: 10.5326/JAAHA-MS-6646. | |
| 2017 | Brunner, M.A.T., Jagannathan, V., Waluk, D.P., Roosje, P., Linek, M., Panakova, L., Leeb, T., Wiener, D.J., Welle, M.M. : |
| Novel insights into the pathways regulating the canine hair cycle and their deregulation in alopecia X. PLoS One 12:e0186469, 2017. Pubmed reference: 29065140. DOI: 10.1371/journal.pone.0186469. | |
| 2016 | Outerbridge, C.A., White, S.D., Affolter, V.K. : |
| Alopecia universalis in a dog with testicular neoplasia. Vet Dermatol 27:513, 2016. Pubmed reference: 27644142. DOI: 10.1111/vde.12380. | |
| 2015 | Berger, D.J., Lewis, T.P., Schick, A.E., Miller, R.I., Loeffler, D.G. : |
| Canine alopecia secondary to human topical hormone replacement therapy in six dogs. J Am Anim Hosp Assoc 51:136-42, 2015. Pubmed reference: 25695561. DOI: 10.5326/JAAHA-MS-6247. | |
| Stoll, S., Dietlin, C., Nett-Mettler, C.S. : | |
| Microneedling as a successful treatment for alopecia X in two Pomeranian siblings. Vet Dermatol 26:387-90, e88, 2015. Pubmed reference: 26175132. DOI: 10.1111/vde.12236. | |
| 2012 | [No authors listed] : |
| Applied dermatology: Postcard presentation: a miniature pinscher with alopecia. Compend Contin Educ Vet 34:E4, 2012. Pubmed reference: 23713156. | |
| Müntener, T., Schuepbach-Regula, G., Frank, L., Rüfenacht, S., Welle, M.M. : | |
| Canine noninflammatory alopecia: a comprehensive evaluation of common and distinguishing histological characteristics. Vet Dermatol 23:206-e44, 2012. Pubmed reference: 22575019. DOI: 10.1111/j.1365-3164.2012.01049.x. | |
| 2008 | Mausberg, E.M., Drögemüller, C., Dolf, G., Rüfenacht, S., Welle, M., Leeb, T. : |
| Exclusion of patched homolog 2 (PTCH2) as a candidate gene for alopecia X in Pomeranians and Keeshonden. Vet Rec 163:121-3, 2008. Pubmed reference: 18660523. DOI: 10.1136/vr.163.4.121. | |
| 2007 | Cerundolo, R., Lloyd, D.H., Vaessen, M.M., Mol, J.A., Kooistra, H.S., Rijnberk, A. : |
| Alopecia in pomeranians and miniature poodles in association with high urinary corticoid:creatinine ratios and resistance to glucocorticoid feedback. Vet Rec 160:393-7, 2007. Pubmed reference: 17384290. DOI: 10.1136/vr.160.12.393. | |
| Mausberg, E.M., Drögemuller, C., Rüfenacht, S., Welle, M., Roosje, P., Suter, M., Leeb, T. : | |
| [Inherited alopecia X in Pomeranians]. Dtsch Tierarztl Wochenschr 114:129-34, 2007. Pubmed reference: 17484499. | |
| Mausberg, E.M., Drögemüller, C., Leeb, T., Dolf, G., Rüfenacht, S., Welle, M. : | |
| Evaluation of the CTSL2 gene as a candidate gene for alopecia X in Pomeranians and Keeshonden. Anim Biotechnol 18:291-6, 2007. Pubmed reference: 17934903. DOI: 10.1080/10495390701547461. | |
| 2006 | Frank, L.A., Donnell, R.L., Kania, S.A. : |
| Oestrogen receptor evaluation in Pomeranian dogs with hair cycle arrest (alopecia X) on melatonin supplementation. Vet Dermatol 17:252-8, 2006. Pubmed reference: 16827668. DOI: 10.1111/j.1365-3164.2006.00520.x. | |
| 2005 | Bassett, RJ., Burton, GG., Robson, DC. : |
| Recurrent flank alopecia in a Tibetan Terrier. Aust Vet J 83:276-9, 2005. Pubmed reference: 15957387. | |
| Cerundolo, R., Mauldin, EA., Goldschmidt, MH., Beyerlein, SL., Refsal, KR., Oliver, JW. : | |
| Adult-onset hair loss in Chesapeake Bay retrievers: a clinical and histological study. Vet Dermatol 16:39-46, 2005. Pubmed reference: 15725104. DOI: 10.1111/j.1365-3164.2005.00432.x. | |
| Frank, LA. : | |
| Growth hormone-responsive alopecia in dogs. J Am Vet Med Assoc 226:1494-7, 2005. Pubmed reference: 15881999. | |
| 2004 | Frank, LA., Hnilica, KA., Oliver, JW. : |
| Adrenal steroid hormone concentrations in dogs with hair cycle arrest (Alopecia X) before and during treatment with melatonin and mitotane. Vet Dermatol 15:278-84, 2004. Pubmed reference: 15500479. DOI: 10.1111/j.1365-3164.2004.00372.x. | |
| 2003 | Frank, L.A., Hnilica, K.A., Rohrbach, B.W., Oliver, J.W. : |
| Retrospective evaluation of sex hormones and steroid hormone intermediates in dogs with alopecia Veterinary Dermatology 14:91-7, 2003. Pubmed reference: 12662266. | |
| 2002 | Takada, K., Kitamura, H., Takiguchi, M., Saito, M., Hashimoto, A. : |
| Cloning of canine 21-hydroxylase gene and its polymorphic analysis as a candidate gene for congenital adrenal hyperplasia-like syndrome in Pomeranians Res Vet Sci 73:159-63, 2002. Pubmed reference: 12204635. DOI: 10.1016/s0034-5288(02)00070-x. | |
| 2001 | Lloyd, D.H., Cerundolo, R. : |
| Alopecia X in dogs. Vet Rec 148:60, 2001. Pubmed reference: 11202560. | |
| 2000 | Cerundolo, R., Lloyd, D.H., McNeil, P.E., Evans, H. : |
| An analysis of factors underlying hypotrichosis and alopecia in Irish Water Spaniels in the United Kingdom (vol 11, pg 107, 2000) Veterinary Dermatology 11:313-314, 2000. | |
| Cerundolo, R., Lloyd, D.H., McNeil, P.E., Evans, H. : | |
| An analysis of factors underlying hypotrichosis and alopecia in Irish Water spaniels in the United Kingdom Vet Dermatol 11:107-122, 2000. Pubmed reference: 34645005. DOI: 10.1046/j.1365-3164.2000.00180.x. | |
| 1999 | De, Jonghe, S.R., Ducatelle, R.V., Mattheeuws, D.R. : |
| Trachyonychia associated with alopecia areata in a Rhodesian Ridgeback Veterinary Dermatology 10:123-126, 1999. | |
| Stratakis, C.A., Rennert, O.M. : | |
| Congenital adrenal hyperplasia: molecular genetics and alternative approaches to treatment. Crit Rev Clin Lab Sci 36:329-63, 1999. Pubmed reference: 10486704. DOI: 10.1080/10408369991239222. | |
| 1998 | Cerundolo, R., Lloyd, D. : |
| Alopecia X in Chows, Pomeranians and Samoyeds Veterinary Record 143:176, 1998. Pubmed reference: 9746955. | |
| 1997 | Declercq, J. : |
| Alopecia in German Shepherds [Dutch] Vlaams Diergeneeskundig Tijdschrift 66:97, 1997. | |
| 1996 | Curtis, C.F., Evans, H., Lloyd, D.H. : |
| Investigation of the reproductive and growth hormone status of dogs affected by idiopathic recurrent flank alopecia Journal of Small Animal Practice 37:417-422, 1996. Pubmed reference: 8887201. | |
| 1995 | Allan, F.J., Jones, B.R., Purdie, E.C. : |
| Endocrine alopecia in a Miniature Poodle New Zealand Veterinary Journal 43:110-113, 1995. | |
| Miller, W.H., Scott, D.W. : | |
| Follicular dysplasia of the portuguese water dog Veterinary Dermatology 6:67-74, 1995. | |
| Waldman, L. : | |
| Seasonal flank alopecia in affenpinschers Journal of Small Animal Practice 36:271-273, 1995. Pubmed reference: 7650925. | |
| 1994 | Vandenbroek, A.H.M. : |
| Fat Absorption in Female Boxer Dogs with Undiagnosed Hormonal Alopecia Veterinary Record 134:277-278, 1994. Pubmed reference: 8197698. | |
| 1991 | Miller, W.H. : |
| Alopecia Associated with Coat Color Dilution in 2 Yorkshire Terriers, One Saluki, and One Mix-Breed Dog Journal of the American Animal Hospital Association 27:39-43, 1991. | |
| 1990 | Schmeitzel, L.P., Lothrop, C.D. : |
| Hormonal abnormalities in Pomeranians with normal coat and in Pomeranians with growth hormone-responsive dermatosis. J Am Vet Med Assoc 197:1333-41, 1990. Pubmed reference: 2176197. | |
| 1989 | Coward, P.S. : |
| A Familial Alopecia Veterinary Record 125:609-610, 1989. Pubmed reference: 2609495. | |
| 1967 | Dämmrich, K. : |
| [On alopecia in dogs]. Berl Munch Tierarztl Wochenschr 80:373-7, 1967. Pubmed reference: 5628512. |
Edit History
- Created by Mohammad Shariflou on 23 Jul 2007
- Changed by Frank Nicholas on 05 Aug 2013
- Changed by Imke Tammen2 on 11 Sep 2022
- Changed by Imke Tammen2 on 12 Aug 2023
- Changed by Imke Tammen2 on 02 Oct 2024