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OMIA:000042-10036 : Analphalipoproteinaemia, ABCA1-related in Mesocricetus auratus (golden hamster)

In other species: chicken

Categories: Homeostasis / metabolism phene

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 205400 (trait) , 600046 (gene)

Links to relevant human diseases in MONDO:

Single-gene trait/disorder: yes

Disease-related: yes

Key variant known: no

Species summary: Wei et al. (2019) generated ABCA1 knockout hamsters using CRISPR/CAS9 technology. This study involves gene edited or genetically modified organisms (GMO).

Genetic engineering: Yes - variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
Abca1 ATP binding cassette subfamily A member 1 Mesocricetus auratus NW_024429184.1 (6896955..7021643) Abca1 Ensembl, NCBI gene

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Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2026). OMIA:000042-10036: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2026 Liu, C., Zheng, J., Shi, S., Chen, J., Liu, G., Huang, W., Xian, X., Wang, Y., Fan, J., Zhu, P., Yang, X. :
ABCA1 deficiency-induced cholesterol accumulation aggravates colonic epithelial injury in knockout hamsters. Animal Model Exp Med , 2026. Pubmed reference: 42885393. DOI: 10.1002/ame2.70301.
2019 Wei, L., Shi, H., Lin, X., Zhang, X., Wang, Y., Liu, G., Xian, X. :
Impact of cholesterol on ischemic stroke in different human-like hamster models: A new animal model for ischemic stroke study. Cells 8:1028, 2019. Pubmed reference: 31487778. DOI: 10.3390/cells8091028.

Edit History


  • Created by Imke Tammen on 18 Oct 2026
  • Changed by Imke Tammen on 18 Oct 2026