OMIA:000123-9031 : Blood group system E in Gallus gallus
In other species: pig
Categories: Haematopoietic system phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: yes
Mode of inheritance: Autosomal co-dominant
Considered a defect: no
Key variant known: no
Key variant is published: no
Cross-species summary: Each blood group system consists of a set of blood types, each of which corresponds to a particular antigen (usually a glycoprotein) on the surface of red blood cells. The different types within a system are the result of the action of different alleles at a locus that usually encodes an enzyme that catalyses the creation of the feature of the glycoprotein unique to that type, e.g. the presence of a particular sugar at the end of a short chain of sugars.
Inheritance: Briles et al. (1959) confirmed the existence of four loci (blood group systems), namely A, B, D, and E, with some evidence of tight linkage between A and E.
Mapping: Fulton et al. (2022): "Genome-wide association studies, sequence analysis, and sequence-derived single-nucleotide polymorphism information for known A and/or E system alleles show ... [that the] best match for the E blood system is the avian equivalent of FCAMR (Fc fragment of IgA and IgM receptor)." Genotyping data for 10 SNP was used to identify 9 haplotypes (H01-H08). Haplotypes H02 and H03 ware associated with several blood system E serological alleles.
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|FCAMR||Gallus gallus||-||no genomic information (-..-)||FCAMR||Ensembl|
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2022||Fulton, J.E., Drobik-Czwarno, W., Wolc, A., McCarron, A.M., Lund, A.R., Schmidt, C.J., Taylor, R.L. :|
|The chicken A and E blood systems arise from genetic variation in and around the regulators of complement activation region. J Immunol 209:1128-1137, 2022. Pubmed reference: 35977798 . DOI: 10.4049/jimmunol.2101010.|
|1997||Kopti, F., Briles, R.W., Briles, W.E. :|
|Immunogenetics of the A-E alloantigen complex. Poult Sci 76:1688-97, 1997. Pubmed reference: 9438283 .|
|1984||Briles, W.E. :|
|Early chicken blood group investigations. Immunogenetics 20:217-26, 1984. Pubmed reference: 6088392 .|
|1970||Seet, C.P., Briles, C.O. :|
|The association of the A, B and E parental blood group system genotypes with fertility and hatchability in chickens. Poult Sci 49:922-6, 1970. Pubmed reference: 5485484 .|
|1959||Briles, C.O., McGibbon, W.H., Irwin, M.R. :|
|Additional Alleles Affecting Red Blood Cell Antigens in the Chicken. Genetics 44:955-65, 1959. Pubmed reference: 17247871 .|
- Created by Frank Nicholas on 06 Sep 2005
- Changed by Frank Nicholas on 14 Oct 2011
- Changed by Imke Tammen2 on 05 May 2023