OMIA:000123-9031 : Blood group system E in Gallus gallus (chicken) |
In other species: pig
Categories: Haematopoietic system phene
Mendelian trait/disorder: yes
Mode of inheritance: Autosomal co-dominant
Disease-related: no
Key variant known: no
Key variant is published: no
Cross-species summary: Each blood group system consists of a set of blood types, each of which corresponds to a particular antigen (usually a glycoprotein) on the surface of red blood cells. The different types within a system are the result of the action of different alleles at a locus that usually encodes an enzyme that catalyses the creation of the feature of the glycoprotein unique to that type, e.g. the presence of a particular sugar at the end of a short chain of sugars.
Inheritance: Briles et al. (1959) confirmed the existence of four loci (blood group systems), namely A, B, D, and E, with some evidence of tight linkage between A and E.
Mapping: Fulton et al. (2022): "Genome-wide association studies, sequence analysis, and sequence-derived single-nucleotide polymorphism information for known A and/or E system alleles show ... [that the] best match for the E blood system is the avian equivalent of FCAMR (Fc fragment of IgA and IgM receptor)." Genotyping data for 10 SNP was used to identify 9 haplotypes (H01-H08). Haplotypes H02 and H03 ware associated with several blood system E serological alleles.
Associated gene:
Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
---|---|---|---|---|---|---|
FCAMR | Gallus gallus | 26 | NC_006113.2 (2408483..2406654) | FCAMR | Homologene, Ensembl , NCBI gene |
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:000123-9031: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2022 | Fulton, J.E., Drobik-Czwarno, W., Wolc, A., McCarron, A.M., Lund, A.R., Schmidt, C.J., Taylor, R.L. : |
The chicken A and E blood systems arise from genetic variation in and around the regulators of complement activation region. J Immunol 209:1128-1137, 2022. Pubmed reference: 35977798. DOI: 10.4049/jimmunol.2101010. | |
2016 | Taylor, R.L., Medarova, Z., Briles, W.E. : |
Immune effects of chicken non-MHC alloantigens. Poult Sci 95:447-57, 2016. Pubmed reference: 26527702. DOI: 10.3382/ps/pev331. | |
1997 | Kopti, F., Briles, R.W., Briles, W.E. : |
Immunogenetics of the A-E alloantigen complex. Poult Sci 76:1688-97, 1997. Pubmed reference: 9438283. | |
1984 | Briles, W.E. : |
Early chicken blood group investigations. Immunogenetics 20:217-26, 1984. Pubmed reference: 6088392. | |
1970 | Seet, C.P., Briles, C.O. : |
The association of the A, B and E parental blood group system genotypes with fertility and hatchability in chickens. Poult Sci 49:922-6, 1970. Pubmed reference: 5485484. | |
1959 | Briles, C.O., McGibbon, W.H., Irwin, M.R. : |
Additional Alleles Affecting Red Blood Cell Antigens in the Chicken. Genetics 44:955-65, 1959. Pubmed reference: 17247871. |
Edit History
- Created by Frank Nicholas on 06 Sep 2005
- Changed by Frank Nicholas on 14 Oct 2011
- Changed by Imke Tammen2 on 05 May 2023