OMIA 000189-93934 : Chondrodystrophy in Coturnix japonica

In other species: chicken , rabbit , turkey , dog , cattle , California condor , pig

Possibly relevant human trait(s) and/or gene(s) (MIM number): 156530

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Recessive Lethal

Considered a defect: yes

Key variant known: no

Species-specific symbol: ch

History: This disorder was first reported by Collins et al. (1968)

Inheritance: Collins et al. (1968) reported autosomal recessive inheritance, with embryonic lethality.

Clinical features: As reported by Collins et al. (1968), "a normally shaped head and neck, and normal eyes. The upper mandible was shortened and sometimes curved. The lower mandible was deformed and markedly shortened and occasionally absent. The limbs were shortened and the tibiae and tarso-metatarsi bent. Ventral body surface hemorrhages were frequently present." They also reported that the trait is "lethal at 8 to 10 days of incubation."

Reference


1968 Collins, W.M., Abplanalp, H., Yoshida, S. :
Early embryonic chondrodystrophy in Japanese quail. J Hered 59:248-50, 1968. Pubmed reference: 5708631.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 09 Nov 2012