OMIA 000350-9031 : Eudiplopodia in Gallus gallus

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Recessive

Considered a defect: yes

Key variant known: no

Species-specific symbol: eu

Mapping: Robb et al. (2011) mapped this trait to chromosome GGA 5q (25,679,935 - 26,751,804)

Clinical features: "Homozygotes (-/-) have extra digits (5–9) on the dorsal surfaces of the limb buds, which develop into extra, scaled bidorsal toes on the feet with conical nails and occasional dorsal knobs or digits on the wings; expression is variable; temperature sensitive phenotype" (Robb et al., 2011)

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2011 Robb, EA., Gitter, CL., Cheng, HH., Delany, ME. :
Chromosomal mapping and candidate gene discovery of chicken developmental mutants and genome-wide variation analysis of MHC congenics. J Hered 102:141-56, 2011. Pubmed reference: 21273214. DOI: 10.1093/jhered/esq122.
1993 Abbott, UK., Pisenti, JM. :
Making the connection: exploring classical concepts in normal and abnormal limb development using contemporary approaches. Prog Clin Biol Res 383A:99-112, 1993. Pubmed reference: 8302913.
1986 Carrington, JL., Fallon, JF. :
Experimental manipulation leading to induction of dorsal ectodermal ridges on normal limb buds results in a phenocopy of the Eudiplopodia chick mutant. Dev Biol 116:130-7, 1986. Pubmed reference: 3732603.
1971 Fraser, RA., Abbott, UK. :
Studies on limb morphogenesis. VI. Experiments with early stages of the polydactylous mutant Eudiplopodia. J Exp Zool 176:237-48, 1971. Pubmed reference: 5559230. DOI: 10.1002/jez.1401760209.
Fraser, RA., Abbott, UK. :
Studies on limb morphogenesis. V. The expression of Eudiplopodia and its experimental modification. J Exp Zool 176:219-36, 1971. Pubmed reference: 5559229. DOI: 10.1002/jez.1401760208.
1964 Goetinck, PF. :
Studies on limb morphogenesis. II. Experiments with the polydactylous mutant eudiplopodia Dev Biol 10:71-91, 1964. Pubmed reference: 14206971.
1959 Rosenblatt, L.S., Kreutziger, G.O., Taylor, L.W. :
Eudiplopodia Poultry Science 38:1242 only, 1959.

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  • Created by Frank Nicholas on 26 Feb 2011