OMIA 000438-9796 : Haemophilia B in Equus caballus
In other species: domestic cat , dog , pig Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 306900 (trait) , 300746 (gene) Mendelian trait/disorder: unknown Considered a defect: yes Cross-species summary: Also called factor IX deficiency or Christmas disease. This is one of the two X-linked bleeding disorders, haemophilia A being the other. The fact that these two disorders are X-linked in all species reported to date provides strong support for Ohno's suggestion that the X chromosome has been highly conserved throughout evolution.
|1956||Sjolin, K.E. :|
|Lack of Christmas factor in horse plasma. Nature 178:153, 1956. Pubmed reference: 13348654.|
- Created by Frank Nicholas on 19 Jan 2016