OMIA:000729-9823 : Teat / nipple, inverted in Sus scrofa (pig)

In other species: taurine cattle

Categories: Endocrine / exocrine gland phene (incl mammary gland)

Possibly relevant human trait(s) and/or gene(s) (MIM number): 163600 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: no

Mode of inheritance: Multifactorial

Considered a defect: yes

Key variant known: no

Species-specific name: Inverted teat defect

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2009). OMIA:000729-9823: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2017 Chalkias, H., Jonas, E., Andersson, L.S., Jacobson, M., de Koning, D.J., Lundeheim, N., Lindgren, G. :
Identification of novel candidate genes for the inverted teat defect in sows using a genome-wide marker panel. J Appl Genet 58:249-259, 2017. Pubmed reference: 28050760. DOI: 10.1007/s13353-016-0382-1.
2014 Chalkias, H., Ekman, E., Lundeheim, N., Rydhmer, L., Jacobson, M. :
Inverted teats (Mammillae invertitae) in gilts - effect on piglet survival and growth rate. J Anim Sci 92:2587-94, 2014. Pubmed reference: 24671590. DOI: 10.2527/jas.2013-7387.
2013 Chomwisarutkun, K., Murani, E., Brunner, R., Ponsuksili, S., Wimmers, K. :
QTL region-specific microarrays reveal differential expression of positional candidate genes of signaling pathways associated with the liability for the inverted teat defect. Anim Genet 44:139-48, 2013. Pubmed reference: 22690698. DOI: 10.1111/j.1365-2052.2012.02378.x.
2012 Chomwisarutkun, K., Murani, E., Ponsuksili, S., Wimmers, K. :
Microarray analysis reveals genes and functional networks relevant to the predisposition to inverted teats in pigs. J Anim Sci 90:1-15, 2012. Pubmed reference: 21856889. DOI: 10.2527/jas.2011-4269.
2009 Tetzlaff, S., Murani, E., Schellander, K., Ponsuksili, S., Wimmers, K. :
Differential expression of growth factors and their receptors indicates their involvement in the inverted teat defect in pigs. J Anim Sci 87:3451-7, 2009. Pubmed reference: 19648501. DOI: 10.2527/jas.2008-1660.
2008 Jonas, E., Schreinemachers, H.J., Kleinw├Ąchter, T., Un, C., Oltmanns, I., Tetzlaff, S., Jennen, D., Tesfaye, D., Ponsuksili, S., Murani, E., Juengst, H., Tholen, E., Schellander, K., Wimmers, K. :
QTL for the heritable inverted teat defect in pigs. Mamm Genome 19:127-38, 2008. Pubmed reference: 18219525. DOI: 10.1007/s00335-007-9086-5.
1995 Mayer, J., Pirchner, F. :
Asymmetry and Inverted Nipples in Gilts Archiv Fur Tierzucht - Archives of Animal Breeding 38:87-91, 1995.
1981 Clayton, G.A., Powell, J.C., Hiley, P.G. :
Inheritance of teat number and teat inversion in pigs Animal Production 33:299-304, 1981.
1980 Done, J.T. :
Teat deficiencies in pigs Veterinary Annual 20:246-254, 1980.
1977 Molenat, M., Thibault, B. :
Heritabilite du nombre de fausses tetines chez la truie :69-73, 1977.
Venev, I. :
The incidence and genetic determination of cratered teats in pigs [Bulgarian] Zhivotnovdni Nauki 14:65-71, 1977.
1971 Holmqvist, L. :
Inverted teats [Swedish] Svinskotsel 61:7-11, 1971.
1965 Parizek, M., Kudelka, E., Groch, L. :
Hereditary of defective nipples in sows and their transmission by breeders Sbornik Vysoke Skoly Zemedelske Brne, Series B 13:301-312, 1965.
1957 Fischer, H. :
Inverted nipple, an inherited defect in swine Hemera Zoa 64:237-238, 1957.
1934 Nordby, J.E. :
Congenital defects in the mammae of swine Journal of Heredity 25:499-502, 1934.

Edit History

  • Created by Frank Nicholas on 01 Dec 2009