OMIA:001003-9823 : Thrombopathia in Sus scrofa (pig)
Categories: Haematopoietic system phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: A disorder of blood coagulation resulting from a failure of ADP release from platelets on stimulation by aggregating factors such as thromboplastin. In a thorough review, Boudreaux (2008) suggests that this disorder "should probably be referred to as CalDAG-GEFI thrombopathias or CalDAG-GEFI platelet disorders". See also entries relating to Thrombopathia, RASGRP2-related (OMIA 002433).
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|1986||Daniels, T.M., Fass, D.N., White, J.G., Bowie, E.J.W. :|
|Platelet storage pool deficiency in pigs Blood 67:1043-1047, 1986. Pubmed reference: 3082387.|
|Thiele, G.L., Rempel, W.E., Fass, D.N., Bowie, E.J.W., Stewart, M., Zoecklein, L. :|
|Inheritance of a new bleeding disease in a herd of swine with Willebrand's disease Journal of Heredity 77:179-182, 1986. Pubmed reference: 3488343.|
- Created by Frank Nicholas on 06 Sep 2005