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OMIA:001191-9615 : Hemivertebrae in Canis lupus familiaris (dog)

In other species: taurine cattle , goat

Categories: Skeleton phene (incl. short stature & teeth)

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 207620 (trait)

Mendelian trait/disorder: no

Mode of inheritance: Multifactorial

Disease-related: yes

Key variant known: no

Inheritance: As reported by Schlensker and Distl (2015), "Heritability estimates for the number and grade of hemivertebrae were 0.58 and 0.53, respectively. The number of coccygeal vertebrae showed a heritability estimate of 0.35. In addition, the number of coccygeal vertebrae was negatively correlated with the number and grade of hemivertebrae. The prevalence of hemivertebrae could increase if dogs with shorter tails are preferentially selected for breeding purposes."

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2015). OMIA:001191-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2024 De Decker, S., Rohdin, C., Gutierrez-Quintana, R. :
Vertebral and spinal malformations in small brachycephalic dog breeds: Current knowledge and remaining questions. Vet J 304:S1090-0233(24)00034-0:106095, 2024. Pubmed reference: 38458418. DOI: 10.1016/j.tvjl.2024.106095.
Estevam, M.V., Toniollo, G.H., Apparicio, M. :
The most common congenital malformations in dogs: Literature review and practical guide. Res Vet Sci 171:S0034-5288(24)00096-1:105230, 2024. Pubmed reference: 38492280. DOI: 10.1016/j.rvsc.2024.105230.
Grapes, N., Bertram, S., Gonçalves, R., De Decker, S. :
Prevalence of discospondylitis and association with congenital vertebral body malformations in English and French bulldogs. J Vet Intern Med , 2024. Pubmed reference: 39360457. DOI: 10.1111/jvim.17209.
2019 Wyatt, S.E., Lafuente, P., Ter Haar, G., Packer, R.M.A., Smith, H., De Decker, S. :
Gait analysis in French bulldogs with and without vertebral kyphosis. Vet J 244:45-50, 2019. Pubmed reference: 30825894. DOI: 10.1016/j.tvjl.2018.12.008.
2017 De Rycke, L., Saunders, J.H. :
Congenital anomalies of the vertebrae in dogs. Vlaams Diergeneeskundig Tijdschrift 86:105-118, 2017. DOI: 10.21825/vdt.v86i2.16296.
2015 Schlensker, E., Distl, O. :
Heritability of hemivertebrae in the French bulldog using an animal threshold model. Vet J 207:188-189, 2015. Pubmed reference: 26626092. DOI: 10.1016/j.tvjl.2015.10.044.
2014 Charalambous, M., Jeffery, N.D., Smith, P.M., Goncalves, R., Barker, A., Hayes, G., Ives, E., Vanhaesebrouck, A.E. :
Surgical treatment of dorsal hemivertebrae associated with kyphosis by spinal segmental stabilisation, with or without decompression. Vet J 202:267-73, 2014. Pubmed reference: 25241946. DOI: 10.1016/j.tvjl.2014.08.011.
2007 Jeffery, N.D., Smith, P.M., Talbot, C.E. :
Imaging findings and surgical treatment of hemivertebrae in three dogs. J Am Vet Med Assoc 230:532-6, 2007. Pubmed reference: 17302550. DOI: 10.2460/javma.230.4.532.
2005 Besalti, O., Ozak, A., Pekcan, Z., Eminaga, S. :
Nasca classification of hemivertebra in five dogs. Ir Vet J 58:688-90, 2005. Pubmed reference: 21851666. DOI: 10.1186/2046-0481-58-12-688.
1992 Bailey, C.S., Morgan, J.P. :
Congenital spinal malformations. Vet Clin North Am Small Anim Pract 22:985-1015, 1992. Pubmed reference: 1641930. DOI: 10.1016/s0195-5616(92)50089-4.
1989 Kirberger, RM. :
Congenital malformation and variation of the lumbar vertebrae in a dog. J S Afr Vet Assoc 60:111-2, 1989. Pubmed reference: 2607532.
1982 Kramer, JW., Schiffer, SP., Sande, RD., Rantanen, NW., Whitener, EK. :
Characterization of heritable thoracic hemivertebra of the German shorthaired pointer. J Am Vet Med Assoc 181:814-5, 1982. Pubmed reference: 7141980.
1980 Widmer, W.R. :
Sublaxated hemivertebrae at T5, with spinal cord compression. J Am Vet Med Assoc 176:1017-8, 1980. Pubmed reference: 7380715.
1975 Done, S.H., Drew, R.A., Robins, G.M., Lane, J.G. :
Hemivertebra in the dog: clinical and pathological observations Veterinary Record 96:313-317, 1975. Pubmed reference: 1129930.
1969 Grenn, H.H., Lindo, D.E. :
Hemivertebrae with severe kypho-scoliosis and accompanying deformities in a dog. Can Vet J 10:214-6, 1969. Pubmed reference: 5388275.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 30 Dec 2015