OMIA 001212-9986 : Curvature of distal foreleg in Oryctolagus cuniculus

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Recessive

Considered a defect: yes

Key variant known: no

History: This disorder was first reported by Pearce (1938). The occurrence of the same phenotype in New Zealand white rabbits in South Africa was reported by Pulker et al. (2011).

Inheritance: In two 1960 papers, Pearce presented evidence of single-locus autosomal recessive inheritance.

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2011 Pulker, T., Carstens, A., Williams, J. :
Antebrachial chondrodysplasia in New Zealand white rabbits (Oryctolagus cuniculus). J S Afr Vet Assoc 82:176-8, 2011. Pubmed reference: 22332303.
1960 Pearce, L. :
Hereditary distal foreleg curvature in the rabbit. II. Genetic and Pathological aspects Journal of Experimental Medicine 111:823-829, 1960. Pubmed reference: 13733756.
Pearce, L. :
Hereditary distal foreleg curvature in the rabbit. I. Manifestations and course of the bowing deformity : Genetic studies Journal of Experimental Medicine 111:801-821, 1960. Pubmed reference: 13733755.
1938 Pearce, L. :
Constitutional (inherited) rachitic-like disorders in the rabbit Archives of Pathology 25:763 only, 1938.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 29 Apr 2016