OMIA 001212-9986 : Curvature of distal foreleg in Oryctolagus cuniculus |
Mendelian trait/disorder:
yes
Mode of inheritance:
Autosomal Recessive
Considered a defect:
yes
Key variant known:
no
History:
This disorder was first reported by Pearce (1938). The occurrence of the same phenotype in New Zealand white rabbits in South Africa was reported by Pulker et al. (2011).
Inheritance:
In two 1960 papers, Pearce presented evidence of single-locus autosomal recessive inheritance.
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2011 | Pulker, T., Carstens, A., Williams, J. : | |
| Antebrachial chondrodysplasia in New Zealand white rabbits (Oryctolagus cuniculus). J S Afr Vet Assoc 82:176-8, 2011. Pubmed reference: 22332303. | ||
| 1960 | Pearce, L. : | |
| Hereditary distal foreleg curvature in the rabbit. I. Manifestations and course of the bowing deformity : Genetic studies Journal of Experimental Medicine 111:801-821, 1960. Pubmed reference: 13733755. | ||
| Pearce, L. : | ||
| Hereditary distal foreleg curvature in the rabbit. II. Genetic and Pathological aspects Journal of Experimental Medicine 111:823-829, 1960. Pubmed reference: 13733756. | ||
| 1938 | Pearce, L. : | |
| Constitutional (inherited) rachitic-like disorders in the rabbit Archives of Pathology 25:763 only, 1938. |
Edit History
- Created by Frank Nicholas on 06 Sep 2005
- Changed by Frank Nicholas on 29 Apr 2016