OMIA:001240-9615 : Hyperphosphatasaemia in Canis lupus familiaris (dog)

Categories: Haematopoietic system phene

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 171720 (trait) , 239100 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: excess of alkaline phosphatase in the blood

Species-specific description: Lawler et al. (1996) reported the familial occurrence of elevated serum alkaline phosphatase (SAP) in Siberian Huskies.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Breed: Siberian Husky (Dog) (VBO_0201233).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2022). OMIA:001240-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset].


1996 Lawler, D.F., Keltner, D.G., Hoffman, W.E., Nachreiner, R.F., Hegstad, R.L., Herndon, P.A., Fisher, B.J. :
Benign familial hyperphosphatasemia in Siberian Huskies American Journal of Veterinary Research 57:612-617, 1996. Pubmed reference: 8723869.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Imke Tammen2 on 23 Oct 2022