OMIA:001279-9823 : Hypotrichosis, recessive in Sus scrofa (pig)
In other species: dog
Categories: Integument (skin) phene
Possibly relevant human trait(s) and/or gene(s) (MIM number): 607591 (gene)
Links to MONDO diseases: No links.
Mendelian trait/disorder: yes
Mode of inheritance: Autosomal recessive
Considered a defect: yes
Key variant known: no
Cross-species summary: Recessive form of lack of hair growth
Inheritance: Roberts and Carroll (1931) provided convincing evidence of autosomal recessive inheritance of hairlessness. It seems very likely that the causative mutation is at a different locus from that which gives rise to "Hypotrichosis, dominant" (MIA 001278) in pigs. However, breeding trials to test non-allelism have not been reported.
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|1931||Roberts, E., Carroll, E. :|
|The inheritance of hairlessness in swine Journal of Heredity 22:125-132, 1931.|
|1918||Hart, E.B., Steenbock, H. :|
|Thyroid hyperplasia and the relation of iodine to the hairless pig malady Journal of Biological Chemistry 33:313-323, 1918.|
- Created by Frank Nicholas on 06 Sep 2005
- Changed by Frank Nicholas on 14 Feb 2012