OMIA:001407-9615 : Lipofuscinosis in Canis lupus familiaris (dog)

In other species: taurine cattle

Categories: Lysosomal storage disease , Renal / urinary system phene

Single-gene trait/disorder: unknown

Disease-related: unknown

Cross-species summary: Accumulation of lipofuscin (brownish granules), a lipid-containing product of lysosomal digestion, within cells. Normally observed in aged animals, but increased amounts of lipofuscin can be accumulated in cells in genetic or non-genetic conditions. 

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Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2025). OMIA:001407-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

Reference

2025 Fujikawa, R., Yasuno, K., Imaoka, M., Hakamata, S., Honda, K., Okado, K., Shimoda, H., Tsuchiya, Y. :
Canine generalized ceroid lipofuscinosis characterized by predominant deposition in pancreatic acinar cells and intestinal smooth muscle cells. J Toxicol Pathol 38:263-271, 2025. Pubmed reference: 41080080. DOI: 10.1293/tox.2025-0049.

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  • Created by Imke Tammen2 on 19 Oct 2025