OMIA 001559-9940 : Fecundity, Embrapa, FecG(E) in Ovis aries
Pérez-Ruiz et al. (2020) reported the same allele having a major effect on fecundity in the Mexican Pelibuey breed.Breeds: Brazilian Santa Inês, Mexican Pelibuey. Associated gene:
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|GDF9||growth differentiation factor 9||Ovis aries||5||NC_040256.1 (46547527..46544800)||GDF9||Homologene, Ensembl, NCBI gene|
By default, variants are sorted chronologically by year of publication, to provide a historical perspective. Readers can re-sort on any column by clicking on the column header. Click it again to sort in a descending order. To create a multiple-field sort, hold down Shift while clicking on the second, third etc relevant column headers.
WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
|Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Year Published||PubMed ID(s)||Acknowledgements|
|Brazilian Santa Inês Mexican Pelibuey||Fecundity, Embrapa, FecG||GDF9||FecG(E)||missense||Oar_v3.1||5||g.41841362T>G||c.1034T>G||p.F345C||2020||31961953 20528846||Variant coordinates obtained from or confirmed by EBI's Some Effect Predictor (VEP) tool|
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2020||Pérez-Ruiz, E., Gallegos-Sánchez, J., Cortez-Romero, C., Segura-León, O.L., Salinas-Ruíz, J., Salazar-Ortiz, J. :|
|FecG<sup>E</sup> mutation in pelibuey sheep. Anim Genet :, 2020. Pubmed reference: 31961953. DOI: 10.1111/age.12912.|
|2013||Juengel, J.L., Davis, G.H., McNatty, K.P. :|
|Using sheep lines with mutations in single genes to better understand ovarian function. Reproduction 146:R111-23, 2013. Pubmed reference: 23801782. DOI: 10.1530/REP-12-0509.|
|Shabir, M., Ganai, T.A., Misra, S.S., Shah, R., Ahmad, T. :|
|Polymorphism study of growth differentiation factor 9B (GDF9B) gene and its association with reproductive traits in sheep. Gene 515:432-8, 2013. Pubmed reference: 23266806. DOI: 10.1016/j.gene.2012.12.018.|
|2011||Silva, BD., Castro, EA., Souza, CJ., Paiva, SR., Sartori, R., Franco, MM., Azevedo, HC., Silva, TA., Vieira, AM., Neves, JP., Melo, EO. :|
|A new polymorphism in the Growth and Differentiation Factor 9 (GDF9) gene is associated with increased ovulation rate and prolificacy in homozygous sheep. Anim Genet 42:89-92, 2011. Pubmed reference: 20528846. DOI: 10.1111/j.1365-2052.2010.02078.x.|
- Created by Frank Nicholas on 22 Mar 2011
- Changed by Frank Nicholas on 08 Oct 2011
- Changed by Frank Nicholas on 09 Dec 2011
- Changed by Frank Nicholas on 28 Jun 2013
- Changed by Frank Nicholas on 24 Jan 2020