OMIA 001565-9913 : Abortion and stillbirth, MIMT1-related in Bos taurus
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|MIMT1||MER1 repeat containing imprinted transcript 1 (non-protein coding)||Bos taurus||-||no genomic information (-..-)||MIMT1||Homologene, Ensembl, NCBI gene|
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WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
Since October 2021, OMIA includes a semiautomated lift-over pipeline to facilitate updates of genomic positions to a recent reference genome position. These changes to genomic positions are not always reflected in the ‘acknowledgements’ or ‘verbal description’ fields in this table.
|OMIA Variant ID||Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Source of Genetic Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Inferred EVA rsID||Year Published||PubMed ID(s)||Acknowledgements|
|644||Finnish Ayrshire||Abortion and stillbirth due to mutation in MIMT1||MIMT1||deletion, gross (>20)||Naturally occurring variant||18||a 110 kb deletion in the MIMT1 gene||2010||21152099|
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2013||Venhoranta, H., Bauersachs, S., Taponen, J., Lohi, H., Taira, T., Andersson, M., Kind, A., Schnieke, A., Flisikowski, K. :|
|Fetal growth restriction caused by MIMT1 deletion alters brain transcriptome in cattle. Int J Dev Neurosci 31:463-7, 2013. Pubmed reference: 23726833. DOI: 10.1016/j.ijdevneu.2013.05.003.|
|2012||Flisikowski, K., Venhoranta, H., Bauersachs, S., Hänninen, R., Fürst, R.W., Saalfrank, A., Ulbrich, S.E., Taponen, J., Lohi, H., Wolf, E., Kind, A., Andersson, M., Schnieke, A. :|
|Truncation of MIMT1 gene in the PEG3 domain leads to major changes in placental gene expression and stillbirth in cattle. Biol Reprod 87:140, 2012. Pubmed reference: 23100617. DOI: 10.1095/biolreprod.112.104240.|
|2010||Flisikowski, K., Venhoranta, H., Nowacka-Woszuk, J., McKay, SD., Flyckt, A., Taponen, J., Schnabel, R., Schwarzenbacher, H., Szczerbal, I., Lohi, H., Fries, R., Taylor, JF., Switonski, M., Andersson, M. :|
|A novel mutation in the maternally imprinted PEG3 domain results in a loss of MIMT1 expression and causes abortions and stillbirths in cattle (Bos taurus). PLoS One 5:e15116, 2010. Pubmed reference: 21152099. DOI: 10.1371/journal.pone.0015116.|
- Created by Frank Nicholas on 17 May 2011
- Changed by Frank Nicholas on 05 Sep 2011
- Changed by Frank Nicholas on 09 Dec 2011
- Changed by Frank Nicholas on 17 May 2013