OMIA 001799-9940 : Fecundity, Olkuska, FecX(O) in Ovis aries
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|BMP15||bone morphogenetic protein 15||Ovis aries||X||NC_040278.1 (56601245..56594761)||BMP15||Homologene, Ensembl, NCBI gene|
By default, variants are sorted chronologically by year of publication, to provide a historical perspective. Readers can re-sort on any column by clicking on the column header. Click it again to sort in a descending order. To create a multiple-field sort, hold down Shift while clicking on the second, third etc relevant column headers.
WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
|Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Year Published||PubMed ID(s)||Acknowledgements|
|Olkuska||Fecundity, Olkuska||BMP15||FecX(O)||missense||Oar_rambouillet_v1.0||X||g.56594934T>G||c.1009A>C||p.(N337H)||Protein and cDNA positions based on NP_001108239.1 and NM_001114767.1, respectively.||2013||23637641||The genomic location on Oar_rambouillet_v1.0 was determined by Katie Eager, EMAI, NSW Department of Primary Industries.|
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2013||Demars, J., Fabre, S., Sarry, J., Rossetti, R., Gilbert, H., Persani, L., Tosser-Klopp, G., Mulsant, P., Nowak, Z., Drobik, W., Martyniuk, E., Bodin, L. :|
|Genome-wide association studies identify two novel BMP15 mutations responsible for an atypical hyperprolificacy phenotype in sheep. PLoS Genet 9:e1003482, 2013. Pubmed reference: 23637641. DOI: 10.1371/journal.pgen.1003482.|
|Juengel, J.L., Davis, G.H., McNatty, K.P. :|
|Using sheep lines with mutations in single genes to better understand ovarian function. Reproduction 146:R111-23, 2013. Pubmed reference: 23801782. DOI: 10.1530/REP-12-0509.|
- Created by Frank Nicholas on 04 May 2013
- Changed by Frank Nicholas on 04 May 2013
- Changed by Frank Nicholas on 16 May 2013