OMIA 001800-9940 : Fecundity, Rasa Aragonesa, FecX(R) in Ovis aries
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|BMP15||bone morphogenetic protein 15||Ovis aries||X||NC_040278.1 (56601245..56594761)||BMP15||Homologene, Ensembl, NCBI gene|
By default, variants are sorted chronologically by year of publication, to provide a historical perspective. Readers can re-sort on any column by clicking on the column header. Click it again to sort in a descending order. To create a multiple-field sort, hold down Shift while clicking on the second, third etc relevant column headers.
WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
|Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Year Published||PubMed ID(s)||Acknowledgements|
|Rasa Aragonesa||Fecundity, Rasa Aragonesa||BMP15||FecXÂ®||deletion, small (<=20)||Oar_rambouillet_v1.0||X||g.56595467_56595483del173||c.460_476del17||p.(W154Nfs*55)||published as c.525_541delTGGGTCCAGAAAAGCCC based on AF236079, protein and cDNA position in table based on NP_001108239.1 and NM_001114767.1, respectively||2008||18355397||The genomic location on Oar_rambouillet_v1.0 was determined by Katie Eager, EMAI, NSW Department of Primary Industries.|
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2013||Juengel, J.L., Davis, G.H., McNatty, K.P. :|
|Using sheep lines with mutations in single genes to better understand ovarian function. Reproduction 146:R111-23, 2013. Pubmed reference: 23801782. DOI: 10.1530/REP-12-0509.|
|2011||Lahoz, B., Alabart, J.L., Jurado, J.J., Calvo, J.H., Martínez-Royo, A., Fantova, E., Folch, J. :|
|Effect of the FecX(R) polymorphism in the bone morphogenetic protein 15 gene on natural or equine chorionic gonadotropin-induced ovulation rate and litter size in Rasa Aragonesa ewes and implications for on-farm application. J Anim Sci 89:3522-30, 2011. Pubmed reference: 21622876. DOI: 10.2527/jas.2010-3828.|
|2009||Martinez-Royo, A., Dervishi, E., Alabart, J.L., Jurado, J.J., Folch, J., Calvo, J.H. :|
|Freemartinism and FecXR allele determination in replacement ewes of the Rasa Aragonesa sheep breed by duplex PCR. Theriogenology 72:1148-52, 2009. Pubmed reference: 19773062. DOI: 10.1016/j.theriogenology.2009.06.029.|
|Monteagudo, L.V., Ponz, R., Tejedor, M.T., Laviña, A., Sierra, I. :|
|A 17 bp deletion in the Bone Morphogenetic Protein 15 (BMP15) gene is associated to increased prolificacy in the Rasa Aragonesa sheep breed. Anim Reprod Sci 110:139-46, 2009. Pubmed reference: 18282670. DOI: 10.1016/j.anireprosci.2008.01.005.|
|2008||Martinez-Royo, A., Jurado, J.J., Smulders, J.P., Martí, J.I., Alabart, J.L., Roche, A., Fantova, E., Bodin, L., Mulsant, P., Serrano, M., Folch, J., Calvo, J.H. :|
|A deletion in the bone morphogenetic protein 15 gene causes sterility and increased prolificacy in Rasa Aragonesa sheep. Anim Genet 39:294-7, 2008. Pubmed reference: 18355397. DOI: 10.1111/j.1365-2052.2008.01707.x.|
- Created by Frank Nicholas on 04 May 2013
- Changed by Frank Nicholas on 04 May 2013