OMIA 001898-9796 : Metabolic syndrome in Equus caballus

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Also known as Insulin resistance or Insulin dysregulation.


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2020 Cash, C.M., Fitzgerald, D.M., Spence, R.J., de Laat, M.A. :
Preliminary analysis of the FAM174A gene suggests it lacks a strong association with equine metabolic syndrome in ponies. Domest Anim Endocrinol 72:106439, 2020. Pubmed reference: 32169753. DOI: 10.1016/j.domaniend.2020.106439.
Roy, M.M., Norton, E.M., Rendahl, A.K., Schultz, N.E., McFarlane, D., Geor, R.J., Mickelson, J.R., McCue, M.E. :
Assessment of the FAM174A 11G allele as a risk allele for equine metabolic syndrome. Anim Genet 51:607-610, 2020. Pubmed reference: 32412131. DOI: 10.1111/age.12952.
Wallis, N., Raffan, E. :
The genetic basis of obesity and related metabolic diseases in humans and companion animals. Genes 11:1378, 2020. Pubmed reference: 33233816. DOI: 10.3390/genes11111378.
2019 Loos, C.M.M., Dorsch, S.C., Elzinga, S.E., Brewster-Barnes, T., Vanzant, E.S., Adams, A.A., Urschel, K.L. :
A high protein meal affects plasma insulin concentrations and amino acid metabolism in horses with equine metabolic syndrome. Vet J 251:105341, 2019. Pubmed reference: 31492392. DOI: 10.1016/j.tvjl.2019.105341.
Norton, E., Schultz, N., Geor, R., McFarlane, D., Mickelson, J., McCue, M. :
Genome-Wide Association Analyses of Equine Metabolic Syndrome Phenotypes in Welsh Ponies and Morgan Horses. Genes (Basel) 10:, 2019. Pubmed reference: 31698676. DOI: 10.3390/genes10110893.
Norton, E.M., Schultz, N.E., Rendahl, A.K., Geor, R.J., Mickelson, J.R., McCue, M.E., Norton, E.M., Schultz, N.E., Rendahl, A.K., Geor, R.J., Mickelson, J.R., McCue, M.E. :
Heritability of metabolic traits associated with equine metabolic syndrome in Welsh ponies and Morgan horses. Equine Vet J 51:475-480, 2019. Pubmed reference: 30472742. DOI: 10.1111/evj.13053.
Ragno, V.M., Zello, G.A., Klein, C.D., Montgomery, J.B. :
From table to stable: A comparative review of selected aspects of human and equine metabolic syndrome. J Equine Vet Sci 79:131-138, 2019. Pubmed reference: 31405493. DOI: 10.1016/j.jevs.2019.06.003.
Rodríguez-Sanz, C.E., Sevane, N., Dunner, S. :
Genetics of equine metabolic syndrome. Vet Rec 185:148, 2019. Pubmed reference: 31371685. DOI: 10.1136/vr.l4725.
2017 Lewis, S.L., Holl, H.M., Streeter, C., Posbergh, C., Schanbacher, B.J., Place, N.J., Mallicote, M.F., Long, M.T., Brooks, S.A. :
Genomewide association study reveals a risk locus for equine metabolic syndrome in the Arabian horse. J Anim Sci 95:1071-1079, 2017. Pubmed reference: 28380523. DOI: 10.2527/jas.2016.1221.
2015 Morgan, R., Keen, J., McGowan, C. :
Equine metabolic syndrome. Vet Rec 177:173-9, 2015. Pubmed reference: 26273009. DOI: 10.1136/vr.103226.
2012 Johnson, P.J., Wiedmeyer, C.E., LaCarrubba, A., Ganjam, V.K., Messer, N.T. :
Diabetes, insulin resistance, and metabolic syndrome in horses. J Diabetes Sci Technol 6:534-40, 2012. Pubmed reference: 22768883.
2011 Frank, N. :
Equine metabolic syndrome. Vet Clin North Am Equine Pract 27:73-92, 2011. Pubmed reference: 21392655. DOI: 10.1016/j.cveq.2010.12.004.
2010 Frank, N., Geor, R.J., Bailey, S.R., Durham, A.E., Johnson, P.J. :
Equine metabolic syndrome. J Vet Intern Med 24:467-75, 2010. Pubmed reference: 20384947. DOI: 10.1111/j.1939-1676.2010.0503.x.
2002 Johnson, P.J. :
The equine metabolic syndrome peripheral Cushing's syndrome. Vet Clin North Am Equine Pract 18:271-93, 2002. Pubmed reference: 15635908. DOI: 10.1016/s0749-0739(02)00006-8.

Edit History

  • Created by Carrie Finno on 11 Dec 2013
  • Changed by Carrie Finno on 11 Dec 2013
  • Changed by Imke Tammen2 on 22 Aug 2021
  • Changed by Imke Tammen2 on 28 Aug 2021