OMIA:001903-9940 : Skeletal dysplasia with craniofacial deformity and disproportionate dwarfism in Ovis aries (sheep)

Categories: Skeleton phene (incl. short stature & teeth)

Mendelian trait/disorder: unknown

Considered a defect: yes

History: This disorder was first reported by Dantas et al. (2013)

Inheritance: Dantas et al. (2013) mentioned the possibility of autosomal incompletely dominant inheritance but no supporting data were provided.

Clinical features: As reported by Dantas et al. (2013), "Dwarf lambs were much smaller than normal, with short legs, a domed head with retruded muzzle and protruded mandible, sternal deformities and exophthalmic eyes situated more laterally in the face than normal."

Prevalence: As reported by Dantas et al. (2013), " In a flock of 68 ewes and three rams of the Cabugi breed, 134 lambs were born over a 4-year period. Of these, 14 (10.4%) had marked cranial abnormalities and dwarfism and died or were humanely destroyed, 43 (32%) had a normal face and 77 (57.5%) had the short face characteristic of the breed".

Breed: Cabugi, Brazil (Sheep) (VBO_0016875).
Breeds in which the phene has been documented. (If a likely causal variant has been documented for the phene, see the variant table breeds in which the variant has been reported).

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2014). OMIA:001903-9940: Online Mendelian Inheritance in Animals (OMIA) [dataset].


2013 Dantas, F.P., Medeiros, G.X., Figueiredo, A.P., Thompson, K., Riet-Correa, F. :
Skeletal Dysplasia with Craniofacial Deformity and Disproportionate Dwarfism in Hair Sheep of Northeastern Brazil. J Comp Pathol 150:245-52, 2013. Pubmed reference: 24447571. DOI: 10.1016/j.jcpa.2013.11.208.

Edit History

  • Created by Frank Nicholas on 25 Jan 2014
  • Changed by Frank Nicholas on 25 Jan 2014
  • Changed by Frank Nicholas on 29 Jan 2014