OMIA 002241-9823 : Neurofibromatosis, type 1 in Sus scrofa |
Possibly relevant human trait(s) and/or gene(s) (MIM number):
162200
Mendelian trait/disorder:
yes
Considered a defect:
yes
Key variant known:
no
Species-specific description:
Using "recombinant adeno-associated virus–mediated (rAAV-mediated) gene targeting and somatic cell nuclear transfer (SCNT)", White et al. (2018) created mini pigs with a deletion of exon 42 of the NF1 gene, as a model of NF1 in humans. These animals are genetically-modified organisms (GMO).
Associated gene:
| Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
|---|---|---|---|---|---|---|
| NF1 | neurofibromin 1 | Sus scrofa | 12 | NC_010454.4 (43754205..43487098) | NF1 | Homologene, Ensembl, NCBI gene |
Edit History
- Created by Frank Nicholas on 03 Feb 2020
- Changed by Frank Nicholas on 03 Feb 2020