OMIA:002299-9615 : Leukemia, chronic myelomonocytic in Canis lupus familiaris

Categories: Neoplasm

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 607785 (trait) , 189980 (gene)

Links to MONDO diseases: No links.

Mendelian trait/disorder: no

Mode of inheritance: Somatic mutation

Considered a defect: yes

Key variant known: yes

Year key variant first reported: 2013

Species-specific name: Chronic myelomonocytic leukemia

Species-specific symbol: CMML

Associated genes:

Symbol Description Species Chr Location OMIA gene details page Other Links
BCR breakpoint cluster region Canis lupus familiaris 26 NC_051830.1 (29260365..29385328) BCR Homologene, Ensembl , NCBI gene
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase Canis lupus familiaris 9 NC_051813.1 (54162127..54019016) ABL1 Homologene, Ensembl , NCBI gene


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2013 Culver, S., Ito, D., Borst, L., Bell, J.S., Modiano, J.F., Breen, M. :
Molecular characterization of canine BCR-ABL-positive chronic myelomonocytic leukemia before and after chemotherapy. Vet Clin Pathol 42:314-22, 2013. Pubmed reference: 23800034 . DOI: 10.1111/vcp.12055.
2007 Hiraoka, H., Hisasue, M., Nagashima, N., Miyama, T., Tanimoto, T., Watanabe, M., Itamoto, K., Mizuno, T., Inokuma, H., Okuda, M. :
A dog with myelodysplastic syndrome: chronic myelomonocytic leukemia. J Vet Med Sci 69:665-8, 2007. Pubmed reference: 17611368 . DOI: 10.1292/jvms.69.665.

Edit History

  • Changed by Imke Tammen2 on 08 Dec 2020
  • Created by Imke Tammen2 on 08 Dec 2020
  • Changed by Imke Tammen2 on 10 Dec 2020