OMIA:002306-9925 : Fecundity, BMP15-related in Capra hircus (goat)

In other species: Atlantic salmon , pig , sheep

Categories: Reproductive system phene

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 300247 (gene) , 300510 (trait)

Single-gene trait/disorder: yes

Disease-related: no

Key variant known: no

Genetic engineering: Yes - in addition to the occurrence of natural variants, variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing

Contact us

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Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2025). OMIA:002306-9925: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2025 Faris, A.S., Rodrigues, K.F., Zeshan, B., Sarker, S., Candyrine, S.C.L., Rahman, M.M., Kalam, M.A., Bhuiyan, M.S.A. :
Polymorphism analysis of GDF9 and BMP15 genes and their association with litter size in crossbreed goats in Malaysia. Trop Anim Health Prod 57:195, 2025. Pubmed reference: 40299199. DOI: 10.1007/s11250-025-04460-1.
Hajian, M., Pirali, A., Moghaddam, S.H.H., Moradi-Hajidavaloo, R., Varnosfaderani, S.R., Jozi, M., Izadi, T., Tanhaie-Vash, N., Kues, W., Nasr-Esfahani, M.H., Jafarpour, F., Eghbalsaied, S. :
Efficient gene editing of BMP15, GDF9, and MSTN-but not the imprinted CLPG gene-in goat embryos via electrotransfection and handmade cloning. Funct Integr Genomics 25:150, 2025. Pubmed reference: 40637794. DOI: 10.1007/s10142-025-01644-8.
2024 Gholizadeh, M., Mohammadnezhad, M. :
Genetic insights into litter size in goats: A meta-analysis of KISS1 and BMP15 SNP variants. Anim Reprod Sci 271:S0378-4320(24)00232-X:107632, 2024. Pubmed reference: 39532003. DOI: 10.1016/j.anireprosci.2024.107632.
Montgomery, G.W. :
Genetic regulation of ovulation rate and multiple births. Reprod Fertil Dev 36:RD24083, 2024. Pubmed reference: 39222471. DOI: 10.1071/RD24083.
2023 Song, T., Liu, Y., Cuomu, R., Tan, Y., A Wang, C., De, J., Cao, X., Zeng, X. :
Polymorphisms analysis of BMP15, GDF9 and BMPR1B in Tibetan Cashmere Goat (Capra hircus). Genes (Basel) 14:1102, 2023. Pubmed reference: 37239462. DOI: 10.3390/genes14051102.
2022 Zergani, E., Rashidi, A., Rostamzadeh, J., Razmkabir, M., Tetens, J. :
Meta-analysis of association between c.963A>G single-nucleotide polymorphism on BMP15 gene and litter size in goats. Arch Anim Breed 65:309-318, 2022. Pubmed reference: 36755958. DOI: 10.5194/aab-65-309-2022.
2017 Jalbani, M.A., Kaleri, H.A., Baloch, A.H., Bangulzai, N., Bugti, A.G., Ashraf, F., Kaleri, R.R., Jan, M., Bugti, G.A., Khosa, A.N. :
Study of BMP15 gene polymorphisim in Lehri goat breed of Balochistan. Journal of Applied Environmental and Biological Sciences 7:84-89, 2017.
2014 Feng, T., Chu, M.X., Cao, G.L., Huang, D.W., DI, R., Qiu-Yue Liu, Q.Y., Pan, Z.Y., Jin, M., Zhang, Y.J. :
Screening for S32G mutation of BMP15 gene in 18 goat breeds. Turk J Vet Anim Sci. 38:463–446, 2014.
2013 Pramod, R.K., Sharma, S.K., Singhi, A., Pan, S., Mitra, A. :
Differential ovarian morphometry and follicular expression of BMP15, GDF9 and BMPR1B influence the prolificacy in goat. Reprod Domest Anim 48:803-9, 2013. Pubmed reference: 23581245. DOI: 10.1111/rda.12165.
2010 Dong, C.H., Du, L.X. :
Polymorphism Analysis of BMP15 Gene Related to Reproduction Trait of Goat Breeds in Shandong Province. 2010; Chin J Zool. 45:59–69, 2010.
2009 Feng, T., Zhao, Y.Z., Chu, M.X., Di, R., Zhang, Y.J., Fang, L. :
Bone Morphogenetic Protein15 as a candidate gene for prolificacy of Jining Grey goat. Chin J Vet Sci 40:468–475, 2009.
2007 Chu, M.X., Jiao, C.L., He, Y.Q., Wang, J.Y., Liu, Z.H., Chen, G.H. :
Association between PCR-SSCP of bone morphogenetic protein 15 gene and prolificacy in Jining Grey goats. Anim Biotechnol 18:263-74, 2007. Pubmed reference: 17934900. DOI: 10.1080/10495390701331114.
Jiao, C.L., Chu, M.X., Wang, J.Y., Fang, L., Ye, S. :
Cloning and sequence analysis of exon 2 of BMP15 gene in Jining Grey goats. Chin J Vet Sc 34:52-55, 2007.

Edit History


  • Created by Imke Tammen2 on 20 Feb 2023
  • Changed by Imke Tammen2 on 12 Jul 2025