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OMIA:002393-9615 : Keratoconjunctivitis sicca, immune-mediated in Canis lupus familiaris (dog)

Categories: Vision / eye phene

Mendelian trait/disorder: no

Mode of inheritance: Multifactorial

Disease-related: yes

Key variant known: no

Species-specific name: Keratoconjunctivitis sicca (KCS) is an abnormality of the tear film attributed to deficiency of the aqueous portion of the tears. Progressive KCS may result in ocular surface irritation and/or vision impairment via corneal opacification. Also called dry eye.

Species-specific description: Genetics Committee of the American College of Veterinary Opthalmologists: Keratoconjunctivitis sicca (KCS) is "an abnormality of the tear film attributed to deficiency of the aqueous portion of the tears. Progressive KCS may result in ocular surface irritation and/or vision impairment via corneal opacification. Also called dry eye."

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2024). OMIA:002393-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2024 Rajaei, S.M., Faghihi, H., Zahirinia, F. :
The Shih Tzu eye: Ophthalmic findings of 1000 eyes. Vet Ophthalmol , 2024. Pubmed reference: 38169085. DOI: 10.1111/vop.13182.
2021 Genetics Committee of the American College of Veterinary Opthalmologists :
The Blue Book: Ocular disorders presumed to be inherited in purebred dogs. 13th Edition https://ofa.org/wp-content/uploads/2022/10/ACVO-Blue-Book-2021.pdf , 2021.
2020 Smith, S.M., Holt, E., Aguirre, G.D. :
Conjunctival staining with lissamine green as a predictor of tear film deficiency in dogs. Vet Ophthalmol 23:624-631, 2020. Pubmed reference: 32386097. DOI: 10.1111/vop.12762.
2015 Dodi, P.L. :
Immune-mediated keratoconjunctivitis sicca in dogs: current perspectives on management. Vet Med (Auckl) 6:341-347, 2015. Pubmed reference: 30101119. DOI: 10.2147/VMRR.S66705.
2008 Williams, D.L. :
Immunopathogenesis of keratoconjunctivitis sicca in the dog. Vet Clin North Am Small Anim Pract 38:251-68, vi, 2008. Pubmed reference: 18299006. DOI: 10.1016/j.cvsm.2007.12.002.

Edit History


  • Created by Imke Tammen2 on 22 Aug 2021
  • Changed by Imke Tammen2 on 22 Aug 2021
  • Changed by Imke Tammen2 on 17 Jun 2023
  • Changed by Imke Tammen2 on 09 Jan 2024