OMIA 002467-9823 : Muscle growth, IGF2-related in Sus scrofa |
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers):
147470 (gene)
,
616489 (trait)
Mendelian trait/disorder:
unknown
Considered a defect:
no
Species-specific description:
This phene includes references to studies involving genetically modified organisms (GMO).
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2021 | Wang, D., Pu, Y., Li, Y., Pan, D., Wang, S., Tian, W., Ma, Y., Jiang, L. : | |
| Comprehensive analysis of lncRNAs involved in skeletal muscle development in ZBED6-knockout Bama pigs. BMC Genomics 22:593, 2021. Pubmed reference: 34348644. DOI: 10.1186/s12864-021-07881-y. | ||
| 2019 | Liu, X., Liu, H., Wang, M., Li, R., Zeng, J., Mo, D., Cong, P., Liu, X., Chen, Y., He, Z. : | |
| Disruption of the ZBED6 binding site in intron 3 of IGF2 by CRISPR/Cas9 leads to enhanced muscle development in Liang Guang Small Spotted pigs. Transgenic Res 28:141-150, 2019. Pubmed reference: 30488155. DOI: 10.1007/s11248-018-0107-9. | ||
| 2018 | Xiang, G., Ren, J., Hai, T., Fu, R., Yu, D., Wang, J., Li, W., Wang, H., Zhou, Q. : | |
| Editing porcine IGF2 regulatory element improved meat production in Chinese Bama pigs. Cell Mol Life Sci 75:4619-4628, 2018. Pubmed reference: 30259067. DOI: 10.1007/s00018-018-2917-6. | ||
| 2012 | Aslan, O., Hamill, R.M., Davey, G., McBryan, J., Mullen, A.M., Gispert, M., Sweeney, T. : | |
| Variation in the IGF2 gene promoter region is associated with intramuscular fat content in porcine skeletal muscle. Mol Biol Rep 39:4101-10, 2012. Pubmed reference: 21779802. DOI: 10.1007/s11033-011-1192-5. | ||
| Burgos, C., Galve, A., Moreno, C., Altarriba, J., Reina, R., García, C., López-Buesa, P. : | ||
| The effects of two alleles of IGF2 on fat content in pig carcasses and pork. Meat Sci 90:309-13, 2012. Pubmed reference: 21907500. DOI: 10.1016/j.meatsci.2011.07.016. | ||
| 2011 | Boysen, T.J., Tetens, J., Thaller, G. : | |
| Evidence for additional functional genetic variation within the porcine IGF2 gene affecting body composition traits in an experimental Piétrain × Large White/Landrace cross. Animal 5:672-7, 2011. Pubmed reference: 22439990. DOI: 10.1017/S1751731110002466. | ||
| Braunschweig, M.H., Owczarek-Lipska, M., Stahlberger-Saitbekova, N. : | ||
| Relationship of porcine IGF2 imprinting status to DNA methylation at the H19 DMD and the IGF2 DMRs 1 and 2. BMC Genet 12:47, 2011. Pubmed reference: 21575277. DOI: 10.1186/1471-2156-12-47. | ||
| 2010 | Fontanesi, L., Speroni, C., Buttazzoni, L., Scotti, E., Dall'Olio, S., Nanni Costa, L., Davoli, R., Russo, V. : | |
| The insulin-like growth factor 2 (IGF2) gene intron3-g.3072G>A polymorphism is not the only Sus scrofa chromosome 2p mutation affecting meat production and carcass traits in pigs: evidence from the effects of a cathepsin D (CTSD) gene polymorphism. J Anim Sci 88:2235-45, 2010. Pubmed reference: 20382874. DOI: 10.2527/jas.2009-2560. | ||
| Hou, G., Wang, D., Guan, S., Zeng, H., Huang, X., Ma, Y. : | ||
| Associated analysis of single nucleotide polymorphisms of IGF2 gene's exon 8 with growth traits in Wuzhishan pig. Mol Biol Rep 37:497-500, 2010. Pubmed reference: 19701694. DOI: 10.1007/s11033-009-9681-5. | ||
| Stinckens, A., Mathur, P., Janssens, S., Bruggeman, V., Onagbesan, O.M., Schroyen, M., Spincemaille, G., Decuypere, E., Georges, M., Buys, N. : | ||
| Indirect effect of IGF2 intron3 g.3072G>A mutation on prolificacy in sows. Anim Genet 41:493-8, 2010. Pubmed reference: 20394605. DOI: 10.1111/j.1365-2052.2010.02040.x. | ||
| 2009 | Oczkowicz, M., Tyra, M., Walinowicz, K., Rózycki, M., Rejduch, B. : | |
| Known mutation (A3072G) in intron 3 of the IGF2 gene is associated with growth and carcass composition in Polish pig breeds. J Appl Genet 50:257-9, 2009. Pubmed reference: 19638682. DOI: 10.1007/BF03195681. | ||
| 2008 | Yu, D.B., He, Z.L., Zhang, W.F., Jia, X.X., Qiu, X.S., Wang, L.Y., Huang, R.H., Liu, H.L. : | |
| [The genetic effects of IGF2 gene intron3 variance in pigs]. Yi Chuan 30:87-93, 2008. Pubmed reference: 18244908. | ||
| 2003 | Van Laere, A.S., Nguyen, M., Braunschweig, M., Nezer, C., Collette, C., Moreau, L., Archibald, A.L., Haley, C.S., Buys, N., Tally, M., Andersson, G., Georges, M., Andersson, L. : | |
| A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig. Nature 425:832-6, 2003. Pubmed reference: 14574411. DOI: 10.1038/nature02064. | ||
| 1999 | Nezer, C., Moreau, L., Brouwers, B., Coppieters, W., Detilleux, J., Hanset, R., Karim, L., Kvasz, A., Leroy, P., Georges, M. : | |
| An imprinted QTL with major effect on muscle mass and fat deposition maps to the IGF2 locus in pigs. Nat Genet 21:155-6, 1999. Pubmed reference: 9988262. DOI: 10.1038/5935. |
Edit History
- Created by Imke Tammen2 on 03 Nov 2021
- Changed by Imke Tammen2 on 03 Nov 2021
- Changed by Imke Tammen2 on 11 Jan 2022